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Marine Microalgae with Anti-Cancer Properties
Martínez Andrade, Kevin A ; Lauritano, Chiara ; Romano, Giovanna ; Ianora, Adrianna
Marine drugs, 2018-05, Vol.16 (5), p.165
[Periódico revisado por pares]
Switzerland: MDPI AG
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Título:
Marine Microalgae with Anti-Cancer Properties
Autor:
Martínez Andrade, Kevin A
;
Lauritano, Chiara
;
Romano, Giovanna
;
Ianora, Adrianna
Assuntos:
Algae
;
Anticancer properties
;
Antineoplastic Agents - chemistry
;
Antineoplastic Agents - pharmacology
;
Antineoplastic Agents - therapeutic use
;
Antitumor agents
;
Biological activity
;
Biological Products - chemistry
;
Biological Products - pharmacology
;
Biological Products - therapeutic use
;
Cancer
;
Carotenoids
;
Cell Proliferation - drug effects
;
Chemical compounds
;
Clinical trials
;
Clinical Trials, Phase III as Topic
;
Dietary Supplements
;
Drug Screening Assays, Antitumor
;
Fatty acids
;
Fine chemicals
;
Functional foods & nutraceuticals
;
Humans
;
Lipids
;
Medical research
;
Microalgae
;
Microalgae - chemistry
;
Neoplasms - drug therapy
;
Organic chemistry
;
Pharmacology
;
Pigments
;
Polysaccharides
;
Primary production
;
Properties
;
Review
;
Saccharides
;
Tumor cell lines
;
Vitamins
É parte de:
Marine drugs, 2018-05, Vol.16 (5), p.165
Notas:
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição:
Cancer is the leading cause of death globally and finding new therapeutic agents for cancer treatment remains a major challenge in the pursuit for a cure. This paper presents an overview on microalgae with anti-cancer activities. Microalgae are eukaryotic unicellular plants that contribute up to 40% of global primary productivity. They are excellent sources of pigments, lipids, carotenoids, omega-3 fatty acids, polysaccharides, vitamins and other fine chemicals, and there is an increasing demand for their use as nutraceuticals and food supplements. Some microalgae are also reported as having anti-cancer activity. In this review, we report the microalgal species that have shown anti-cancer properties, the cancer cell lines affected by algae and the concentrations of compounds/extracts tested to induce arrest of cell growth. We also report the mediums used for growing microalgae that showed anti-cancer activity and compare the bioactivity of these microalgae with marine anticancer drugs already on the market and in phase III clinical trials. Finally, we discuss why some microalgae can be promising sources of anti-cancer compounds for future development.
Editor:
Switzerland: MDPI AG
Idioma:
Inglês
Links
View this record in MEDLINE/PubMed
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