Idioma:

Prognostic impact of tumor location in colon cancer: the Monitoring of Cancer Incidence in Japan (MCIJ) project

Nakagawa-Senda, Hiroko ; Hori, Megumi ; Matsuda, Tomohiro ; Ito, Hidemi

BMC cancer, 2019-05, Vol.19 (1), p.431-431, Article 431 [Periódico revisado por pares]

England: BioMed Central Ltd

Texto completo disponível

Citações Citado por

Enviar para

Título:
Prognostic impact of tumor location in colon cancer: the Monitoring of Cancer Incidence in Japan (MCIJ) project
Autor: Nakagawa-Senda, Hiroko ; Hori, Megumi ; Matsuda, Tomohiro ; Ito, Hidemi
Assuntos: Adult ; Age ; Aged ; Aged, 80 and over ; Anatomical subsite ; Cancer patients ; Cancer research ; Colon - pathology ; Colon cancer ; Colonic Neoplasms - mortality ; Colonic Neoplasms - pathology ; Colorectal cancer ; Colorectal carcinoma ; Epidemiology ; Female ; Future predictions ; Humans ; Incidence ; Japan - epidemiology ; Male ; Medical prognosis ; Metastasis ; Middle Aged ; Mortality ; Mutation ; Net survival ; Patient outcomes ; Population ; Population-based cancer registries ; Prognosis ; Registries - statistics & numerical data ; Sex ; Survival ; Survival Analysis ; Survival Rate ; Systematic review ; Tumors
É parte de: BMC cancer, 2019-05, Vol.19 (1), p.431-431, Article 431
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Colorectal cancer (CRC) is globally one of the most common cancers. Although studies have found a significant prognostic impact of cancer location for right-sided colon cancers compared with those of the left-side, evidence is lacking in a Japanese population. Therefore, we investigated 5-year net survival in colon cancer by tumor site in a Japanese population. Diagnoses obtained between 2006 and 2008 in 21 population-based cancer registries from the Monitoring of Cancer Incidence in Japan (MCIJ) project were used. Colon cancer patients were categorized as having right-sided (C18.0-18.4) or left-sided colon cancer (C18.5-C18.7). We calculated the 5-year net survival for subjects diagnosed from 2006 until 2008 by anatomical subsite according to sex, age groups, tumor stage at diagnosis. We applied the excess mortality model to calculate excess hazard ratios (EHRs) and 95% confidential intervals (CIs) with and without adjustment for age, sex and cancer stages to evaluate the effect of location of colon cancer. This study analyzed a total of 62,350 colon cancer subjects. Five-year net survivals for subjects with left- and right-sided colon cancer were 74.0% (95% CI, 73.4-74.7%) and 70.4% (95% CI, 69.7-71.0%), respectively. Compared with left-sided colon cancers, the EHR for right-sided colon cancers was 1.20 (95% CI, 1.16-1.25) after adjustment for age, sex and stage. Our study found that the net survival for right-sided colon cancer was significantly lower than that for left-sided colon cancer. The anatomical site of cancer in the colon might be an important stratification factor in future studies of colon cancer.
Editor: England: BioMed Central Ltd
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Anterior Resultado 8 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Prognostic impact of tumor location in colon cancer: the Monitoring of Cancer Incidence in Japan (MCIJ) project

Nakagawa-Senda, Hiroko ; Hori, Megumi ; Matsuda, Tomohiro ; Ito, Hidemi

England: BioMed Central Ltd

Buscando em bases de dados remotas. Favor aguardar.