skip to main content
Idioma:

Immunological and non-immunological mechanisms of allergic diseases in the elderly: biological and clinical characteristics

Di Lorenzo, Gabriele ; Di Bona, Danilo ; Belluzzo, Federica ; Macchia, Luigi

Immunity & ageing, 2017-12, Vol.14 (1), p.23-23, Article 23 [Periódico revisado por pares]

England: BioMed Central Ltd

Texto completo disponível

Citações Citado por
  • Título:
    Immunological and non-immunological mechanisms of allergic diseases in the elderly: biological and clinical characteristics
  • Autor: Di Lorenzo, Gabriele ; Di Bona, Danilo ; Belluzzo, Federica ; Macchia, Luigi
  • Assuntos: Aged ; Allergic conjunctivitis ; Allergic rhinitis ; Asthma ; Care and treatment ; Conjunctivitis ; Elderly ; Hay-fever ; Health aspects ; Immunosenescence ; Review ; Skin diseases
  • É parte de: Immunity & ageing, 2017-12, Vol.14 (1), p.23-23, Article 23
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-3
    content type line 23
    ObjectType-Review-1
  • Descrição: A better hygiene, a Westernized diet, air pollution, climate changes, and other factors that influence host microbiota, a key player in the induction and maintenance of immunoregulatory circuits and tolerance, are thought to be responsible for the increase of allergic diseases observed in the last years. The increase of allergic diseases in elderly is related to the presence of other factors as several comorbidities that should interfere with the development and the type of allergic reactions. A central role is played by immunosenescence responsible for modifying response to microbiota and triggering inflamm-ageing. In addition, in elderly there is a shift from Th1 responses vs. Th2, hence favouring allergic responses. Better understanding of the mechanisms of immunosenescence and its effects on allergic inflammation will most certainly lead to improved therapy.
  • Editor: England: BioMed Central Ltd
  • Idioma: Inglês
Links
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.