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The cell biology of planar cell polarity

Devenport, Danelle

The Journal of cell biology, 2014-10, Vol.207 (2), p.171-179 [Periódico revisado por pares]

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Título:
The cell biology of planar cell polarity
Autor: Devenport, Danelle
Assuntos: Animals ; Body Patterning ; Cell Communication ; Cell Polarity ; Cells ; Cellular biology ; Cues ; Drosophila - cytology ; Drosophila - embryology ; Models, Biological ; Proteins ; Reviews ; Signal Transduction ; Tissues
É parte de: The Journal of cell biology, 2014-10, Vol.207 (2), p.171-179
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
Descrição: Planar cell polarity (PCP) refers to the coordinated alignment of cell polarity across the tissue plane. Key to the establishment of PCP is asymmetric partitioning of cortical PCP components and intercellular communication to coordinate polarity between neighboring cells. Recent progress has been made toward understanding how protein transport, endocytosis, and intercellular interactions contribute to asymmetric PCP protein localization. Additionally, the functions of gradients and mechanical forces as global cues that bias PCP orientation are beginning to be elucidated. Together, these findings are shedding light on how global cues integrate with local cell interactions to organize cellular polarity at the tissue level.
Editor: United States: Rockefeller University Press
Idioma: Inglês

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