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Relation of Anxiety and Depressive Symptoms to Coronary Artery Calcium (From the ELSA-Brasil Baseline Data)

Santos, Itamar S., PhD ; Bittencourt, Marcio S., PhD ; Rocco, Priscila T., MD ; Pereira, Alexandre C., PhD ; Barreto, Sandhi M., PhD ; Brunoni, André R., PhD ; Goulart, Alessandra C., PhD ; Blaha, Michael J., PhD ; Lotufo, Paulo A., PhD ; Bensenor, Isabela M., PhD

The American journal of cardiology, 2016-07, Vol.118 (2), p.183-187 [Periódico revisado por pares]

United States: Elsevier Inc

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Título:
Relation of Anxiety and Depressive Symptoms to Coronary Artery Calcium (From the ELSA-Brasil Baseline Data)
Autor: Santos, Itamar S., PhD ; Bittencourt, Marcio S., PhD ; Rocco, Priscila T., MD ; Pereira, Alexandre C., PhD ; Barreto, Sandhi M., PhD ; Brunoni, André R., PhD ; Goulart, Alessandra C., PhD ; Blaha, Michael J., PhD ; Lotufo, Paulo A., PhD ; Bensenor, Isabela M., PhD
Assuntos: Adult ; Age ; Aged ; Anxiety ; Anxiety - epidemiology ; Body mass index ; Brazil - epidemiology ; Calcinosis - diagnostic imaging ; Calcinosis - epidemiology ; Calcium ; Cardiovascular ; Cardiovascular disease ; Confidence intervals ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - epidemiology ; Coronary vessels ; Coronary Vessels - diagnostic imaging ; Cross-Sectional Studies ; Depression - epidemiology ; Diabetes ; Family medical history ; Female ; Gender ; Heart attacks ; Humans ; Hypertension ; Logistic Models ; Longitudinal Studies ; Male ; Mental depression ; Mental disorders ; Middle Aged ; Morbidity ; Neuroses ; Obsessive compulsive disorder ; Odds Ratio ; Standard deviation ; Studies ; Tomography, X-Ray Computed ; Variables ; Veins & arteries
É parte de: The American journal of cardiology, 2016-07, Vol.118 (2), p.183-187
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SourceType-Scholarly Journals-1
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Descrição: Abstract Prior studies of the association between symptoms of anxiety or depression and coronary artery calcium (CAC) have produced heterogeneous results. Our aim was to investigate whether psychopathological symptoms were associated with CAC in a cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline. We analyzed data from 4,279 ELSA-Brasil subjects (aged 35 to 74 years) from the São Paulo site without previous cardiovascular disease who underwent CAC score assessment at baseline. Prevalent CAC was defined as a CAC score above zero. Anxiety and depressive symptoms were assessed using the Clinical Interview Schedule – Revised (CIS-R). We built binary logistic regression models to determine whether CIS-R scores, anxiety or depression were associated with prevalent CAC. Prevalent CAC was found in 1,211 (28.3%) individuals. After adjustment for age and sex, a direct association between CIS-R scores and prevalent CAC was revealed (odds ratio [OR] for 1 standard deviation [1-SD] increase: 1.12; 95% confidence interval [95%CI]: 1.04-1.22). This association persisted after multivariate adjustment (OR for 1-SD increase: 1.11; 95%CI: 1.02-1.20). No independent associations were found for specific diagnoses of anxiety or depression and prevalent CAC. In post-hoc models, a significant interaction term (p=0.019), suggested a stronger association in older individuals. In conclusion, psychopathological symptoms were directly associated with coronary atherosclerosis in the ELSA-Brasil baseline in adjusted models, and this association seems to be stronger in older individuals.
Editor: United States: Elsevier Inc
Idioma: Inglês

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Relation of Anxiety and Depressive Symptoms to Coronary Artery Calcium (From the ELSA-Brasil Baseline Data)

Santos, Itamar S., PhD ; Bittencourt, Marcio S., PhD ; Rocco, Priscila T., MD ; Pereira, Alexandre C., PhD ; Barreto, Sandhi M., PhD ; Brunoni, André R., PhD ; Goulart, Alessandra C., PhD ; Blaha, Michael J., PhD ; Lotufo, Paulo A., PhD ; Bensenor, Isabela M., PhD

United States: Elsevier Inc

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