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Relation of Thoracic Aortic and Coronary Artery Calcium to Cardiovascular Risk Factors (from The Brazilian Longitudinal Study of Adult Health [ELSA-Brazil])

Pedrosa, Jesiana F. ; Ribeiro, Antonio Luiz P. ; Santana, Priscila C. ; Araújo, Larissa F. ; Barreto, Sandhi M.

The American journal of cardiology, 2019-12, Vol.124 (11), p.1655-1661 [Periódico revisado por pares]

United States: Elsevier Inc

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Título:
Relation of Thoracic Aortic and Coronary Artery Calcium to Cardiovascular Risk Factors (from The Brazilian Longitudinal Study of Adult Health [ELSA-Brazil])
Autor: Pedrosa, Jesiana F. ; Ribeiro, Antonio Luiz P. ; Santana, Priscila C. ; Araújo, Larissa F. ; Barreto, Sandhi M.
Assuntos: Adult ; Aged ; Antidiabetics ; Antihypertensives ; Aorta ; Aorta, Thoracic - diagnostic imaging ; Aortic Diseases - diagnosis ; Aortic Diseases - epidemiology ; Aortography ; Arteriosclerosis ; Atherosclerosis ; Blood pressure ; Body mass ; Body mass index ; Body size ; Brazil - epidemiology ; Calcification (ectopic) ; Calcium ; Calcium - metabolism ; Cardiovascular diseases ; Cholesterol ; Color ; Computed tomography ; Coronary Angiography - methods ; Coronary artery ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - epidemiology ; Coronary vessels ; Coronary Vessels - diagnostic imaging ; Correlation analysis ; Cross-Sectional Studies ; Density ; Diabetes mellitus ; EKG ; Female ; Follow-Up Studies ; Genetics ; Health risks ; Heart attacks ; Heart diseases ; Hemoglobin ; Humans ; Lipids ; Longitudinal studies ; Low density lipoprotein ; Male ; Men ; Middle Aged ; Morbidity - trends ; Multidetector Computed Tomography ; Multivariate analysis ; Physical activity ; Race ; Regression analysis ; Retrospective Studies ; Risk analysis ; Risk Assessment ; Risk factors ; Sex ; Smoking ; Survival Rate - trends ; Thorax ; Tomography ; Vascular Calcification - diagnosis ; Vascular Calcification - epidemiology ; Veins & arteries ; Womens health
É parte de: The American journal of cardiology, 2019-12, Vol.124 (11), p.1655-1661
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
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Descrição: Thoracic aortic calcium (TAC) and coronary artery calcium (CAC) are associated with an increased risk of cardiovascular disease (CVD) and death. However, risk factors associated with arterial calcium may vary across vascular beds. We verified whether TAC is associated with the same risk factors as is CAC in adults without established CVD. Cross-sectional analysis including 2,433 participants (aged 38 to 78 years) of ELSA-Brasil cohort in Minas Gerais, Brazil. Nonenhanced ECG-gated multislice computed tomography were performed to detect calcium in the thoracic aorta and the coronaries (2015 to 2016). Multivariate logistic regression evaluated the associations of both TAC and CAC with CVD risk factors (smoking, body mass index, physical activity, alcohol intake, family history of CVD, low-density lipoprotein- and high-density lipoprotein-cholesterol, HbA1c, blood pressure, antidiabetic, antihypertensive, and lipid lowering medications). Overall prevalence of TAC and CAC were 69% and 43%, respectively. CAC prevalence was lower among women (31%) than men (56%) (Adjusted odds ratio [OR] 0.30; 0.24 to 0.38). After adjustments, black individuals were less likely to have any CAC as compared with whites (OR 0.63; 0.47 to 0.86). Neither sex, nor race/skin color were statistically associated with TAC. Use of antidiabetic medications remained associated with CAC (OR 1.80; 1.23 to 2.631.01), but not with TAC. All other risk factors, except education, alcohol, physical activity and HbA1c, persisted statistically associated with both TAC and CAC in the final analysis, with small differences in the magnitudes of the ORs. In conclusion, the only disagreements seen in the risk factors associated with CAC and TAC were sex, race/skin color, and use of antidiabetic medications.
Editor: United States: Elsevier Inc
Idioma: Inglês

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Relation of Thoracic Aortic and Coronary Artery Calcium to Cardiovascular Risk Factors (from The Brazilian Longitudinal Study of Adult Health [ELSA-Brazil])

Pedrosa, Jesiana F. ; Ribeiro, Antonio Luiz P. ; Santana, Priscila C. ; Araújo, Larissa F. ; Barreto, Sandhi M.

United States: Elsevier Inc

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