Idioma:

Iron-Catalyzed Trifluoromethylation of Enamide

Rey-Rodriguez, Romain ; Retailleau, Pascal ; Bonnet, Pascal ; Gillaizeau, Isabelle

Chemistry : a European journal, 2015-02, Vol.21 (9), p.3572-3575 [Periódico revisado por pares]

Weinheim: WILEY-VCH Verlag

Texto completo disponível

Citações Citado por

Enviar para

Título:
Iron-Catalyzed Trifluoromethylation of Enamide
Autor: Rey-Rodriguez, Romain ; Retailleau, Pascal ; Bonnet, Pascal ; Gillaizeau, Isabelle
Assuntos: Amides - chemistry ; Catalysis ; Chemical Sciences ; Chemistry ; CH functionalization ; Fluorination ; Functional groups ; Hydrocarbons, Fluorinated - chemistry ; Iron - chemistry ; iron-catalyzed reactions ; Methylation ; Molecular Structure ; Strategy ; synthetic methods ; Togni's reagent ; Tolerances ; Transformations ; trifluoromethylation
É parte de: Chemistry : a European journal, 2015-02, Vol.21 (9), p.3572-3575
Notas: ArticleID:CHEM201406333
LABEX SynOrg - No. ANR-11-LABX-0029
University of Orléans
istex:F0157971F90EB3F21B96851E0BF33082348BC216
ark:/67375/WNG-K2PPLG3Z-P
FEDER COSMI
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Herein the first example of the iron(II)‐catalyzed trifluoromethylation of enamide using mild and simple reaction conditions is reported. The method is cost‐effective and uses the easy‐to‐handle Togni’s reagent as the electrophilic CF3 source. This transformation is totally regioselective at the C3 position of enamides and exhibits broad substrate scope, good functional group tolerance and thus demonstrates its useful application in a late‐stage fluorination strategy. The iron age: The first example of the FeII‐catalyzed trifluoromethylation of enamide using mild and simple reaction conditions is reported (see scheme; EWG=electron‐withdrawing group). The method is cost‐effective and uses the easy‐to‐handle Togni's reagent as the electrophilic CF3 source.
Editor: Weinheim: WILEY-VCH Verlag
Idioma: Inglês

Links

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Iron-Catalyzed Trifluoromethylation of Enamide

Rey-Rodriguez, Romain ; Retailleau, Pascal ; Bonnet, Pascal ; Gillaizeau, Isabelle

Weinheim: WILEY-VCH Verlag

Buscando em bases de dados remotas. Favor aguardar.