Idioma:

Absence of Post-Transplantation Lymphoproliferative Disorder after Allogeneic Blood or Marrow Transplantation Using Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis

Kanakry, Jennifer A ; Kasamon, Yvette L ; Bolaños-Meade, Javier ; Borrello, Ivan M ; Brodsky, Robert A ; Fuchs, Ephraim J ; Ghosh, Nilanjan ; Gladstone, Douglas E ; Gocke, Christopher D ; Huff, Carol Ann ; Kanakry, Christopher G ; Luznik, Leo ; Matsui, William ; Mogri, Huzefa J ; Swinnen, Lode J ; Symons, Heather J ; Jones, Richard J ; Ambinder, Richard F

Biology of blood and marrow transplantation, 2013-10, Vol.19 (10), p.1514-1517

United States: Elsevier Inc

Texto completo disponível

Citações Citado por

Enviar para

Título:
Absence of Post-Transplantation Lymphoproliferative Disorder after Allogeneic Blood or Marrow Transplantation Using Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis
Autor: Kanakry, Jennifer A ; Kasamon, Yvette L ; Bolaños-Meade, Javier ; Borrello, Ivan M ; Brodsky, Robert A ; Fuchs, Ephraim J ; Ghosh, Nilanjan ; Gladstone, Douglas E ; Gocke, Christopher D ; Huff, Carol Ann ; Kanakry, Christopher G ; Luznik, Leo ; Matsui, William ; Mogri, Huzefa J ; Swinnen, Lode J ; Symons, Heather J ; Jones, Richard J ; Ambinder, Richard F
Assuntos: Adolescent ; Adult ; Aged ; Allogeneic blood or marrow transplantation ; Antineoplastic Agents, Alkylating - therapeutic use ; Bone Marrow Transplantation - methods ; Cyclophosphamide - therapeutic use ; Female ; Graft vs Host Disease - drug therapy ; Graft vs Host Disease - prevention & control ; Graft-versus-host disease prophylaxis ; Hematology, Oncology and Palliative Medicine ; Humans ; Immunosuppressive Agents - therapeutic use ; Lymphoma - drug therapy ; Lymphoma - surgery ; Lymphoma - therapy ; Male ; Middle Aged ; Post-transplantation cyclophosphamide ; Post-transplantation lymphoproliferative disorder ; Transplantation, Homologous - methods ; Young Adult
É parte de: Biology of blood and marrow transplantation, 2013-10, Vol.19 (10), p.1514-1517
Descrição: Abstract Immunosuppressive regimens that effectively prevent graft-versus-host disease (GVHD) after allogeneic blood or marrow transplantation (allo-BMT) have been associated with an increased incidence of post-transplantation lymphoproliferative disorder (PTLD) in the first year after transplantation. We evaluated the incidence of PTLD associated with the use of high-dose post-transplantation cyclophosphamide (PTCy) as GVHD prophylaxis. Between 2000 and 2011, a total of 785 adult allo-BMT recipients were given PTCy as GVHD prophylaxis at the Johns Hopkins Hospital, including 313 patients who received PTCy as sole GVHD prophylaxis. HLA-haploidentical or unrelated donor graft transplantation was performed in 526 patients (67%). No cases of PTLD occurred during the first year after allo-BMT in this series. PTLD is a rare occurrence after allo-BMT using PTCy, even in high-risk alternative donor transplantations.
Editor: United States: Elsevier Inc
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Absence of Post-Transplantation Lymphoproliferative Disorder after Allogeneic Blood or Marrow Transplantation Using Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis

United States: Elsevier Inc

Buscando em bases de dados remotas. Favor aguardar.