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Lifetime Risk of Cardiovascular Disease Among Individuals With and Without Diabetes Stratified by Obesity Status in the Framingham Heart Study

Fox, Caroline S ; Pencina, Michael J ; Wilson, Peter W.F ; Paynter, Nina P ; Vasan, Ramachandran S ; D'Agostino, Ralph B. Sr

Diabetes care, 2008-08, Vol.31 (8), p.1582-1584 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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Título:
Lifetime Risk of Cardiovascular Disease Among Individuals With and Without Diabetes Stratified by Obesity Status in the Framingham Heart Study
Autor: Fox, Caroline S ; Pencina, Michael J ; Wilson, Peter W.F ; Paynter, Nina P ; Vasan, Ramachandran S ; D'Agostino, Ralph B. Sr
Assuntos: Aged ; Aged, 80 and over ; Biological and medical sciences ; Cardiovascular disease ; Cardiovascular Diseases - epidemiology ; Diabetes ; Diabetes Complications - epidemiology ; Diabetes. Impaired glucose tolerance ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Epidemiology/Health Services Research ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Female ; Health risk assessment ; Humans ; Male ; Medical sciences ; Metabolic diseases ; Middle Aged ; Miscellaneous ; Mortality ; Obesity ; Obesity - complications ; Obesity - epidemiology ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Risk Assessment ; Time Factors
É parte de: Diabetes care, 2008-08, Vol.31 (8), p.1582-1584
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Corresponding author: Caroline S. Fox, foxca@nhlbi.nih.gov
Published ahead of print at http://care.diabetesjournals.org on 5 May 2008.
The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C Section 1734 solely to indicate this fact.
C.F. had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Descrição: OBJECTIVE:--We assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes. RESEARCH DESIGN AND METHODS--Participants were drawn from the original and offspring cohorts of the Framingham Heart Study. Lifetime (30-year) risk of CVD was assessed using a modified Kaplan-Meier approach adjusting for the competing risk of death, beginning from age 50 years. RESULTS:--Over 30 years, the lifetime risk of CVD among women with diabetes was 54.8% among normal-weight women and 78.8% among obese women. Among normal-weight men with diabetes, the lifetime risk of CVD was 78.6%, whereas it was 86.9% among obese men. CONCLUSIONS:--The lifetime risk of CVD among individuals with diabetes is high, and this relationship is further accentuated with increasing adiposity.
Editor: Alexandria, VA: American Diabetes Association
Idioma: Inglês

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Lifetime Risk of Cardiovascular Disease Among Individuals With and Without Diabetes Stratified by Obesity Status in the Framingham Heart Study

Fox, Caroline S ; Pencina, Michael J ; Wilson, Peter W.F ; Paynter, Nina P ; Vasan, Ramachandran S ; D'Agostino, Ralph B. Sr

Alexandria, VA: American Diabetes Association

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