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Photosensitivity to piroxicam: absence of cross-reaction with tenoxicam

Gonçalo, M. ; Figueiredo, A. ; Tavares, P. ; Fontes Ribeiro, C. A. ; Teixeira, F. ; Polares Baptista, A.

Contact dermatitis, 1992-05, Vol.27 (5), p.287-290 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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Título:
Photosensitivity to piroxicam: absence of cross-reaction with tenoxicam
Autor: Gonçalo, M. ; Figueiredo, A. ; Tavares, P. ; Fontes Ribeiro, C. A. ; Teixeira, F. ; Polares Baptista, A.
Assuntos: Adult ; Aged ; allergen replacement ; Allergy ; Anti-Inflammatory Agents, Non-Steroidal - adverse effects ; Anti-Inflammatory Agents, Non-Steroidal - immunology ; Biological and medical sciences ; chemical basis ; Dermatitis, Photoallergic - etiology ; Dermatitis, Photoallergic - immunology ; Dermatology ; Drug toxicity and drugs side effects treatment ; Female ; Humans ; Life Sciences & Biomedicine ; Male ; Medical sciences ; medicaments. lack of corss-sensitivity ; Middle Aged ; NSAIDs ; Patch Tests ; Pharmacology. Drug treatments ; photosensitivity ; photosensitivity, medicaments. lack of corss‐sensitivity ; piroxicam ; Piroxicam - adverse effects ; Piroxicam - analogs & derivatives ; Piroxicam - immunology ; Science & Technology ; tenoxicam ; thimerosal ; thiosalicylic acid ; Toxicity: skin, dermoskeleton
É parte de: Contact dermatitis, 1992-05, Vol.27 (5), p.287-290
Notas: ArticleID:COD287
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Descrição: We studied 2 groups of patients. One group or 10 patients had a photosensitive eruption to piroxicam. Another group of 24 patients had positive patch test reactions to thimerosal and thiosalicylie acid and had never taken piroxicam or tenoxicam. Patients were patch tested with thimerosal 0.1% pet., thiasalicylic acid 0.1% pet., salicylic acid 2.0% pet., piroxicam 1 and 5% pet. and tenoxicam 1 and 5% pet. photopatch tests were also performed with piroxicam and tenoxicam. All 10 patients with photosensitivity to piroxicam had positive patch tests to thiosalicylic and thiosalicylic acid and 9 of them had positive photopatch tests to ptroxicam. 20 out of 24 patients with positive patch tests to thiosalicylic acid also had positive photopatch tests to Piroxicam. All the patients tested with salicylic add were negative. Out of the 29 patients with positive photopatch tests to piroxicam, none reacted to tenoxicam. In countries with a high incidence of contact sensitivity to thimerosal/thiosalicylic acid, the use of piroxicam should be avoided and replaced by tenoxicam, a drug without reported photosensitivity
Editor: Oxford, UK: Blackwell Publishing Ltd
Idioma: Inglês

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Photosensitivity to piroxicam: absence of cross-reaction with tenoxicam

Gonçalo, M. ; Figueiredo, A. ; Tavares, P. ; Fontes Ribeiro, C. A. ; Teixeira, F. ; Polares Baptista, A.

Oxford, UK: Blackwell Publishing Ltd

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