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NLRP3 Inflammasome and Inflammatory Diseases

Wang, Zheng ; Zhang, Simei ; Xiao, Ying ; Zhang, Wunai ; Wu, Shuai ; Qin, Tao ; Yue, Yangyang ; Qian, Weikun ; Li, Li Cordani, Marco ; Marco Cordani

Oxidative medicine and cellular longevity, 2020, Vol.2020, p.4063562-11 [Periódico revisado por pares]

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Título:
NLRP3 Inflammasome and Inflammatory Diseases
Autor: Wang, Zheng ; Zhang, Simei ; Xiao, Ying ; Zhang, Wunai ; Wu, Shuai ; Qin, Tao ; Yue, Yangyang ; Qian, Weikun ; Li, Li
Cordani, Marco ; Marco Cordani
Assuntos: Atherosclerosis ; Bone marrow ; Cytokines ; Infections ; Inflammation ; Inflammatory diseases ; Mitochondria ; Mitochondrial DNA ; Pathogens ; Proteins ; Researchers ; Review ; Rheumatism
É parte de: Oxidative medicine and cellular longevity, 2020, Vol.2020, p.4063562-11
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Guest Editor: Marco Cordani
Descrição: Almost all human diseases are strongly associated with inflammation, and a deep understanding of the exact mechanism is helpful for treatment. The NLRP3 inflammasome composed of the NLRP3 protein, procaspase-1, and ASC plays a vital role in regulating inflammation. In this review, NLRP3 regulation and activation, its proinflammatory role in inflammatory diseases, interactions with autophagy, and targeted therapeutic approaches in inflammatory diseases will be summarized.
Editor: United States: Hindawi
Idioma: Inglês

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