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Role of microRNAs in the regulation of innate immune cells under neuroinflammatory conditions

Cardoso, Ana L ; Guedes, Joana R ; de Lima, Maria C Pedroso

Current opinion in pharmacology, 2016-02, Vol.26 (C), p.1-9 [Periódico revisado por pares]

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Título:
Role of microRNAs in the regulation of innate immune cells under neuroinflammatory conditions
Autor: Cardoso, Ana L ; Guedes, Joana R ; de Lima, Maria C Pedroso
Assuntos: Animals ; Brain - immunology ; Humans ; Immunity, Innate ; Internal Medicine ; Medical Education ; MicroRNAs - immunology ; Neurogenic Inflammation - immunology ; Neuroimmunomodulation
É parte de: Current opinion in pharmacology, 2016-02, Vol.26 (C), p.1-9
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
USDOE Office of Nuclear Energy (NE), Nuclear Fuel Cycle and Supply Chain
PTDC/BIM-MEC/0651/2012; UID/NEU/04539/2013; SFRH/BD/51677/2011
Descrição: Highlights • Transcriptome studies suggest miRNAs can be used as microglia phenotype markers. • MiR-124 regulates the quiescent state of microglia in the brain. • The immune role of miR-146a and miR-155 depends on the type of brain injury. • Transcription kinetics of miRNAs/target mRNAs control miRNA immune regulatory role.
Editor: England: Elsevier Ltd
Idioma: Inglês

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