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T-kinin is released from T-kininogen by consecutive cleavage by cathespin E-like proteinase and 72 kDa proteinase

Sakamoto, Wataru ; Yoshikawa, Katsumi ; Yokoyama, Atsuro ; Kohri, Masaki

Biochimica et biophysica acta. General subjects, 1986-12, Vol.884 (3), p.607-609 [Periódico revisado por pares]

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Título:
T-kinin is released from T-kininogen by consecutive cleavage by cathespin E-like proteinase and 72 kDa proteinase
Autor: Sakamoto, Wataru ; Yoshikawa, Katsumi ; Yokoyama, Atsuro ; Kohri, Masaki
Assuntos: 72 kDa proteinase ; Cathepsin E-like proteinase ; T-kinin ; T-kininogen
É parte de: Biochimica et biophysica acta. General subjects, 1986-12, Vol.884 (3), p.607-609
Descrição: Using highly purified T-kininogen and cathepsin E-like proteinase and 72 kDa proteinase in rat spleen, the release of T-kinin from T-kininogen was found to occur by consecutive cleavage by cathespin E-like proteinase and 72 kDa proteinase. 72 kDa proteinase seems to be serine proteinase, because it was completely inhibited by diisopropyl fluorophosphate but not by pepstatin, leupeptin and bestatin.
Editor: Elsevier B.V
Idioma: Inglês

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