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Multiple neoplasms in an adolescent child associated with IgA deficiency

Hamoudi, Ala B. ; Ertel, Inta ; Newton, W. A. ; Reiner, Charles B. ; Clatworthy, H. William

Cancer, 1974-04, Vol.33 (4), p.1134-1144 [Periódico revisado por pares]

New York: Wiley Subscription Services, Inc., A Wiley Company

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Título:
Multiple neoplasms in an adolescent child associated with IgA deficiency
Autor: Hamoudi, Ala B. ; Ertel, Inta ; Newton, W. A. ; Reiner, Charles B. ; Clatworthy, H. William
Assuntos: Adenocarcinoma - immunology ; Adenocarcinoma - pathology ; Adolescent ; Adult ; Age Factors ; Astrocytoma - immunology ; Astrocytoma - pathology ; Brain - pathology ; Brain Neoplasms - immunology ; Carcinoma, Squamous Cell - immunology ; Carcinoma, Squamous Cell - pathology ; Child ; Choroid Neoplasms - immunology ; Colon - pathology ; Colonic Neoplasms - immunology ; Colonic Neoplasms - pathology ; Female ; Humans ; Immunoglobulin A ; Immunologic Deficiency Syndromes - complications ; Immunologic Deficiency Syndromes - genetics ; Intestinal Polyps - immunology ; Intestinal Polyps - pathology ; Lymph Nodes - pathology ; Lymphoma, Non-Hodgkin ; Male ; Meninges ; Neoplasm Recurrence, Local ; Neoplasms - genetics ; Neoplasms, Multiple Primary - immunology ; Scalp - pathology ; Spinal Neoplasms ; Thymoma - immunology
É parte de: Cancer, 1974-04, Vol.33 (4), p.1134-1144
Notas: Department of Pediatrics.
Department of Pathology.
Department of Surgery.
ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
Descrição: A report is presented of an unusual occurrence of multiple primary malignant neoplasms in a young girl. Beginning at the age of 10 she had multiple adenomatous polyps removed from the colon over a 2‐year period. One of the polyps had a malignant transformation. During the ensuing 8 years, she developed malignant thymoma, squamous cell carcinoma of the scalp, adenocarcinoma of the colon, which recurred, and choroid tumor of the eye. She died at the age of 20 with malignant astrocytoma of the cerebrum. A brother died at the age of 16 because of lymphoma, lymphocytic, well differentiated, with invasion of the spinal column and meninges. The girl had a serum IgA less than 20% of normal level and her brother had total absence of IgA.
Editor: New York: Wiley Subscription Services, Inc., A Wiley Company
Idioma: Inglês

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Multiple neoplasms in an adolescent child associated with IgA deficiency

Hamoudi, Ala B. ; Ertel, Inta ; Newton, W. A. ; Reiner, Charles B. ; Clatworthy, H. William

New York: Wiley Subscription Services, Inc., A Wiley Company

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