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A New Scoring System for Predicting Ventricular Arrhythmia Risk in Patients with Acute Myocardial Infarction

Sun, Ling ; Han, Bing ; Wang, Yu ; Zhu, Wenwu ; Jiang, Jianguang ; Zou, Ailin ; Chi, Boyu ; Mao, Lipeng ; Ji, Yuan ; Wang, Qingjie ; Tang, Liming

Clinical interventions in aging, 2023-01, Vol.18, p.283-292 [Periódico revisado por pares]

New Zealand: Dove Medical Press Limited

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Título:
A New Scoring System for Predicting Ventricular Arrhythmia Risk in Patients with Acute Myocardial Infarction
Autor: Sun, Ling ; Han, Bing ; Wang, Yu ; Zhu, Wenwu ; Jiang, Jianguang ; Zou, Ailin ; Chi, Boyu ; Mao, Lipeng ; Ji, Yuan ; Wang, Qingjie ; Tang, Liming
Assuntos: Accuracy ; acute myocardial infarction ; Angioplasty ; Area Under Curve ; Arrhythmias, Cardiac - diagnosis ; Calibration ; Cardiac arrhythmia ; Cardiac function ; Complications and side effects ; Creatinine ; Diabetes ; Diabetes Mellitus, Type 2 ; Electrocardiography ; Ethics ; Heart attack ; Heart attacks ; Hospitalization ; Humans ; Medical imaging ; Mortality ; Myocardial Infarction - complications ; Older people ; Original Research ; Potassium ; Prognosis ; Regression analysis ; Risk factors ; risk stratification ; scoring system ; ST Elevation Myocardial Infarction - complications ; Statistical analysis ; Variables ; ventricular flutter and fibrillation ; Ventricular tachycardia
É parte de: Clinical interventions in aging, 2023-01, Vol.18, p.283-292
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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These authors contributed equally to this work
Descrição: In this study, a risk score for ventricular arrhythmias (VA) were evaluated for predicting the risk of ventricular arrhythmia (VA) of acute myocardial infarction (AMI) patients. Patients with AMI were divided into two sets according to whether VA occurred during hospitalization. Another cohort was enrolled for external validation. The area under the curve (AUC) of receiver operating characteristic (ROC) was calculated to evaluate the accuracy of the model. A total of 1493 eligible patients with AMI were enrolled as the training set, of whom 70 (4.7%) developed VA during hospitalization. In-hospital mortality was significantly higher in the VA set than in the non-VA set (31.4% vs 2.7%, P=0.001). The independent predictors of VA in patients with AMI including Killip grade ≥3, STEMI patients, LVEF <50%, frequent premature ventricular beats, serum potassium <3.5 mmol/L, type 2 diabetes, and creatinine level. The AUC of the model for predicting VT/VF in the training set was 0.815 (95% CI: 0.763-0.866). A total of 1149 cases were enrolled from Xuzhou Center Hospital as the external validation set. The AUC of the model in the external validation set for predicting VT/VF was 0.755 (95% CI: 0.687-0.823). Calibration curves indicated a good consistency between the predicted and the observed probabilities of VA in both sets. We have established a clinical prediction risk score for predicting the occurrence of VA in AMI patients. The prediction score is easy to use, performs well and can be used to guide clinical practice.
Editor: New Zealand: Dove Medical Press Limited
Idioma: Inglês

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A New Scoring System for Predicting Ventricular Arrhythmia Risk in Patients with Acute Myocardial Infarction

Sun, Ling ; Han, Bing ; Wang, Yu ; Zhu, Wenwu ; Jiang, Jianguang ; Zou, Ailin ; Chi, Boyu ; Mao, Lipeng ; Ji, Yuan ; Wang, Qingjie ; Tang, Liming

New Zealand: Dove Medical Press Limited

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