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Additional file 6 of Reverse transcriptase inhibition potentiates target therapy in BRAF-mutant melanomas: effects on cell proliferation, apoptosis, DNA-damage, ROS induction and mitochondrial membrane depolarization

Fattore, Luigi ; Malpicci, Debora ; Milite, Ciro ; Castellano, Sabrina ; Sbardella, Gianluca ; Botti, Gerardo ; Ascierto, Paolo A. ; Mancini, Rita ; Ciliberto, Gennaro

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Additional file 6 of Reverse transcriptase inhibition potentiates target therapy in BRAF-mutant melanomas: effects on cell proliferation, apoptosis, DNA-damage, ROS induction and mitochondrial membrane depolarization
Autor: Fattore, Luigi ; Malpicci, Debora ; Milite, Ciro ; Castellano, Sabrina ; Sbardella, Gianluca ; Botti, Gerardo ; Ascierto, Paolo A. ; Mancini, Rita ; Ciliberto, Gennaro
Assuntos: Biochemistry ; Biological Sciences not elsewhere classified ; Cancer ; Cell Biology ; Chemical Sciences not elsewhere classified ; FOS: Biological sciences ; FOS: Chemical sciences ; Genetics ; Medicine ; Molecular Biology ; Pharmacology
Notas: RelationTypeNote: IsSupplementTo -- 10.1186/s12964-020-00633-7
10.1186/s12964-020-00633-7
Descrição: Additional file 5 : Figure S5. SPV122 + MAPKi induce mitochondrial membrane depolarization in A375 cells. Mitochondrial membrane depolarization has been assessed by FACS analyses after 48 h of exposure to encorafenib, MEK162 and/or SPV122.
Editor: figshare
Data de criação/publicação: 2020
Idioma: Inglês

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