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Glyceraldehyde-3-phosphate dehydrogenase as a moonlighting protein in bacteria

Giménez Claudio, Rosa ; Aguilera Gil, Maria Laura ; Ferreira, Elaine ; Aguilar Piera, Juan ; Baldomà Llavinés, Laura ; Badía Palacín, Josefa

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Glyceraldehyde-3-phosphate dehydrogenase as a moonlighting protein in bacteria
Autor: Giménez Claudio, Rosa ; Aguilera Gil, Maria Laura ; Ferreira, Elaine ; Aguilar Piera, Juan ; Baldomà Llavinés, Laura ; Badía Palacín, Josefa
Assuntos: Bacteria ; Bacteris ; Biochemistry ; Bioquímica ; Oxidoreductases
Descrição: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is considered a housekeeping protein that is present in virtually all organisms, where it performs metabolic functions essential for survival. GAPDH plays an essential role in the process of energy production, and is also involved in numerous biological processes. GAPDH belongs to a subset of proteins called moonlighting proteins, in which different functions are associated with a single polypeptide chain. The multifunctionality of GAPDH has been described in pathogenic and probiotic microorganisms, in mammals and in plants. In this review, we summarize the moonlighting role of GAPDH in bacteria. Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704
Editor: Research Signpost
Data de criação/publicação: 2014
Idioma: Inglês

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