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High-Side Digitally Current Controlled Biphasic Bipolar Microstimulator

Hanson, Timothy L. ; Omarsson, Björn ; O'Doherty, Joseph E. ; Peikon, Ian D. ; Lebedev, Mikhail A. ; Nicolelis, Miguel A. L.

IEEE transactions on neural systems and rehabilitation engineering, 2012-05, Vol.20 (3), p.331-340 [Periódico revisado por pares]

United States: IEEE

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Título:
High-Side Digitally Current Controlled Biphasic Bipolar Microstimulator
Autor: Hanson, Timothy L. ; Omarsson, Björn ; O'Doherty, Joseph E. ; Peikon, Ian D. ; Lebedev, Mikhail A. ; Nicolelis, Miguel A. L.
Assuntos: Analog-Digital Conversion ; Animals ; Arm - innervation ; Arm - physiology ; Brain ; Cerebral Cortex - physiology ; cortex ; Current measurement ; Electric Stimulation - adverse effects ; Electric Stimulation - instrumentation ; Electrodes ; Electrodes, Implanted - adverse effects ; Electromyography ; Electronics ; Equipment Design ; Internet ; Macaca mulatta ; microstimulation ; Movement - physiology ; Nanotechnology ; Nerve Tissue - physiology ; Nervous system ; Pulse measurements ; Resistors ; Software ; suppression ; Transistors ; Voltage measurement
É parte de: IEEE transactions on neural systems and rehabilitation engineering, 2012-05, Vol.20 (3), p.331-340
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Electrical stimulation of nervous tissue has been extensively used as both a tool in experimental neuroscience research and as a method for restoring of neural functions in patients suffering from sensory and motor disabilities. In the central nervous system, intracortical microstimulation (ICMS) has been shown to be an effective method for inducing or biasing perception, including visual and tactile sensation. ICMS also holds promise for enabling brain-machine-brain interfaces (BMBIs) by directly writing information into the brain. Here we detail the design of a high-side, digitally current-controlled biphasic, bipolar microstimulator, and describe the validation of the device in vivo. As many applications of this technique, including BMBIs, require recording as well as stimulation, we pay careful attention to isolation of the stimulus channels and parasitic current injection. With the realized device and standard recording hardware - without active artifact rejection - we are able to observe stimulus artifacts of less than 2 ms in duration.
Editor: United States: IEEE
Idioma: Inglês

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High-Side Digitally Current Controlled Biphasic Bipolar Microstimulator

Hanson, Timothy L. ; Omarsson, Björn ; O'Doherty, Joseph E. ; Peikon, Ian D. ; Lebedev, Mikhail A. ; Nicolelis, Miguel A. L.

United States: IEEE

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