Idioma:

Influence of the Macroring Size on the Self-Association Thermodynamics of Cyclodextrins with a Double-Linked Naphthalene at the Secondary Face

González-Álvarez, M. José ; Benito, Juan M ; García Fernández, José M ; Ortiz Mellet, C ; Mendicuti, Francisco

The journal of physical chemistry. B, 2013-05, Vol.117 (18), p.5472-5485 [Periódico revisado por pares]

Washington, DC: American Chemical Society

Texto completo disponível

Citações Citado por

Enviar para

Título:
Influence of the Macroring Size on the Self-Association Thermodynamics of Cyclodextrins with a Double-Linked Naphthalene at the Secondary Face
Autor: González-Álvarez, M. José ; Benito, Juan M ; García Fernández, José M ; Ortiz Mellet, C ; Mendicuti, Francisco
Assuntos: Atomic and molecular physics ; Constants ; Cyclodextrins ; Cyclodextrins - chemistry ; Derivatives ; Dichroism ; Dimerization ; Dimers ; Exact sciences and technology ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Molecular Dynamics Simulation ; Molecular properties and interactions with photons ; Naphthalene ; Naphthalenes - chemistry ; Particle Size ; Physics ; Properties of molecules and molecular ions ; Surface Properties ; Thermodynamics
É parte de: The journal of physical chemistry. B, 2013-05, Vol.117 (18), p.5472-5485
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: The conformational properties and aggregation behavior of two selectively modified cyclomaltooligosaccharides (cyclodextrins, CDs) containing a double-linked 1,8-dimethylnaphthalene cap-like moiety at the secondary face, namely, 2I,3I-O-(1,8-dimetylnaphthalene-α,α′-diyl)-per-O-Me-α- and -γ-cyclodextrins (NmαCD and NmγCD, respectively), in water and in organic solvents were investigated. Both CD derivatives self-associated in water to form dimer species, but the characteristics of the dimerization process and of the resulting dimer strongly depended on the size of the macrocycle. Dimerization constants, thermodynamic parameters upon association, and information about the preferred conformations of the monomer and dimer CD structures were obtained by using NMR, UV–vis, steady-state and time-resolved fluorescence, and circular dichroism experimental techniques, as well as molecular mechanics (MM) and molecular dynamics (MD) simulations. The complexation of 1,8-di(methoxymethyl)naphathalene (oNy) and the heteroassociation of both NmCDs with their permethylated CD partners (mCDs), lacking the aromatic cap, were examined. In addition, the influence of the size of the chromophore moiety on the thermodynamics of self-association was also assessed by comparison of the results obtained for the new naphthalene derivatives with those of the 2I,3I-O-(1,2-xylylene)-modified CD analogues (XmCDs).
Editor: Washington, DC: American Chemical Society
Idioma: Inglês

Links

Voltar para lista de resultados

Anterior Resultado 4 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Influence of the Macroring Size on the Self-Association Thermodynamics of Cyclodextrins with a Double-Linked Naphthalene at the Secondary Face

González-Álvarez, M. José ; Benito, Juan M ; García Fernández, José M ; Ortiz Mellet, C ; Mendicuti, Francisco

Washington, DC: American Chemical Society

Buscando em bases de dados remotas. Favor aguardar.