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Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention

Chandramohan, Daniel ; Zongo, Issaka ; Sagara, Issaka ; Cairns, Matthew ; Yerbanga, Rakiswendé-Serge ; Diarra, Modibo ; Nikièma, Frédéric ; Tapily, Amadou ; Sompougdou, Frédéric ; Issiaka, Djibrilla ; Zoungrana, Charles ; Sanogo, Koualy ; Haro, Alassane ; Kaya, Mahamadou ; Sienou, Abdoul-Aziz ; Traore, Seydou ; Mahamar, Almahamoudou ; Thera, Ismaila ; Diarra, Kalifa ; Dolo, Amagana ; Kuepfer, Irene ; Snell, Paul ; Milligan, Paul ; Ockenhouse, Christian ; Ofori-Anyinam, Opokua ; Tinto, Halidou ; Djimde, Abdoulaye ; Ouédraogo, Jean-Bosco ; Dicko, Alassane ; Greenwood, Brian

The New England journal of medicine, 2021-09, Vol.385 (11), p.1005-1017 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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Título:
Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention
Autor: Chandramohan, Daniel ; Zongo, Issaka ; Sagara, Issaka ; Cairns, Matthew ; Yerbanga, Rakiswendé-Serge ; Diarra, Modibo ; Nikièma, Frédéric ; Tapily, Amadou ; Sompougdou, Frédéric ; Issiaka, Djibrilla ; Zoungrana, Charles ; Sanogo, Koualy ; Haro, Alassane ; Kaya, Mahamadou ; Sienou, Abdoul-Aziz ; Traore, Seydou ; Mahamar, Almahamoudou ; Thera, Ismaila ; Diarra, Kalifa ; Dolo, Amagana ; Kuepfer, Irene ; Snell, Paul ; Milligan, Paul ; Ockenhouse, Christian ; Ofori-Anyinam, Opokua ; Tinto, Halidou ; Djimde, Abdoulaye ; Ouédraogo, Jean-Bosco ; Dicko, Alassane ; Greenwood, Brian
Assuntos: Age ; Amodiaquine ; Amodiaquine - therapeutic use ; Antimalarials - adverse effects ; Antimalarials - therapeutic use ; Burkina Faso - epidemiology ; Chemoprevention ; Children ; Children & youth ; Clinical trials ; Combined Modality Therapy ; Complications ; Double-Blind Method ; Drug Combinations ; Drug therapy ; Drug Therapy, Combination ; Female ; Global Health ; Hepatitis ; Hospitalization - statistics & numerical data ; Humans ; Immunization ; Infant ; Infectious Disease ; Intervention ; Life Sciences ; Malaria ; Malaria vaccine ; Malaria Vaccines - administration & dosage ; Malaria Vaccines - adverse effects ; Malaria, Falciparum - epidemiology ; Malaria, Falciparum - mortality ; Malaria, Falciparum - prevention & control ; Male ; Mali - epidemiology ; Parasitic Infections ; Patient outcomes ; Pharmacists ; Public health ; Pyrimethamine ; Pyrimethamine - therapeutic use ; Santé publique et épidémiologie ; Seasons ; Seizures, Febrile - etiology ; Statistical analysis ; Sulfadoxine ; Sulfadoxine - therapeutic use ; Testing ; Tropical diseases ; Vaccination ; Vaccines
É parte de: The New England journal of medicine, 2021-09, Vol.385 (11), p.1005-1017
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Descrição: This trial assessed the efficacy of the vaccine RTS,S/AS01 E as compared with chemoprevention in preventing malaria. The protective efficacy of RTS,S/AS01 E was noninferior to that of chemoprevention, and the combination of RTS,S/AS01 E and chemoprevention was more effective than either intervention alone.
Editor: United States: Massachusetts Medical Society
Idioma: Inglês

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Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention

United States: Massachusetts Medical Society

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