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Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers

YING JUN CAO ; FLEXNER, Charles W ; BECKER, Stephen ; HENDRIX, Craig W ; DUNAWAY, Shelia ; PARK, Jeong-Gun ; KLINGMAN, Karin ; WIGGINS, Ilene ; CONLEY, Jeanne ; RADEBAUGH, Christine ; KASHUBA, Angela D ; MACFARLAND, Ron

Antimicrobial Agents and Chemotherapy, 2008-05, Vol.52 (5), p.1630-1634 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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Título:
Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers
Autor: YING JUN CAO ; FLEXNER, Charles W ; BECKER, Stephen ; HENDRIX, Craig W ; DUNAWAY, Shelia ; PARK, Jeong-Gun ; KLINGMAN, Karin ; WIGGINS, Ilene ; CONLEY, Jeanne ; RADEBAUGH, Christine ; KASHUBA, Angela D ; MACFARLAND, Ron
Assuntos: Adolescent ; Adult ; Aminoquinolines ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Area Under Curve ; Benzimidazoles ; Biological and medical sciences ; Butylamines ; Dose-Response Relationship, Drug ; Heterocyclic Compounds, 1-Ring ; Heterocyclic Compounds, 1-Ring - adverse effects ; Heterocyclic Compounds, 1-Ring - blood ; Heterocyclic Compounds, 1-Ring - pharmacokinetics ; HIV Protease Inhibitors - pharmacology ; Humans ; Male ; Medical sciences ; Metabolic Clearance Rate ; Middle Aged ; Pharmacology ; Pharmacology. Drug treatments ; Receptors, CXCR4 ; Receptors, CXCR4 - antagonists & inhibitors ; Ritonavir ; Ritonavir - pharmacology
É parte de: Antimicrobial Agents and Chemotherapy, 2008-05, Vol.52 (5), p.1630-1634
Notas: Corresponding author. Mailing address: Osler 501, 600 N. Wolfe Street, Baltimore, MD 21287. Phone: (410) 502-3252. Fax: (410) 614-9978. E-mail: ycao3@jhmi.edu
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Editor: Washington, DC: American Society for Microbiology
Idioma: Inglês

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Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers

YING JUN CAO ; FLEXNER, Charles W ; BECKER, Stephen ; HENDRIX, Craig W ; DUNAWAY, Shelia ; PARK, Jeong-Gun ; KLINGMAN, Karin ; WIGGINS, Ilene ; CONLEY, Jeanne ; RADEBAUGH, Christine ; KASHUBA, Angela D ; MACFARLAND, Ron

Washington, DC: American Society for Microbiology

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