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Genetic analysis of autosomal and Y-specific STRs in the Karimojong population from Uganda

Gusmão, Leonor ; Sánchez-Diz, Paula ; Gomes, Iva ; Alves, Cíntia ; Carracedo, Ángel ; João Prata, Maria ; Amorim, António

International Congress series, 2006-04, Vol.1288, p.213-215 [Periódico revisado por pares]

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Título:
Genetic analysis of autosomal and Y-specific STRs in the Karimojong population from Uganda
Autor: Gusmão, Leonor ; Sánchez-Diz, Paula ; Gomes, Iva ; Alves, Cíntia ; Carracedo, Ángel ; João Prata, Maria ; Amorim, António
Assuntos: Africa ; Autosomal marker ; STR ; Uganda ; Y-chromosome specific marker
É parte de: International Congress series, 2006-04, Vol.1288, p.213-215
Descrição: In this work, 90 individuals living in Karamoja region were typed for 17 autosomal STRs and 40 males were also typed for 12 Y-STRs. Hardy–Weinberg equilibrium was tested for each autosomal locus and no deviations from equilibrium were observed. For autosomal STRs, our sample shows a combined matching probability of 1 in 6.5×1019 individuals and a combined power of exclusion of 0.999999988. Haplotype diversity for Y-STRs was 0.9859 and 32 different haplotypes were detected. Our sample was compared with available autosomal data from sub-Saharan African samples and significant differences were found with Mozambique; Cabinda (Angola); Equatorial Guinea; and with Rwanda. Comparisons with the Y-STR data, revealed large genetic distances between our sample and Mozambique, Cabinda and Equatorial Guinea.
Editor: Elsevier B.V
Idioma: Inglês

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