Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design

Butler, Christopher R ; Brodney, Michael A ; Beck, Elizabeth M ; Barreiro, Gabriela ; Nolan, Charles E ; Pan, Feng ; Vajdos, Felix ; Parris, Kevin ; Varghese, Alison H ; Helal, Christopher J ; Lira, Ricardo ; Doran, Shawn D ; Riddell, David R ; Buzon, Leanne M ; Dutra, Jason K ; Martinez-Alsina, Luis A ; Ogilvie, Kevin ; Murray, John C ; Young, Joseph M ; Atchison, Kevin ; Robshaw, Ashley ; Gonzales, Cathleen ; Wang, Jinlong ; Zhang, Yong ; O’Neill, Brian T

J. Med. Chem, 2015-03, Vol.58 (6), p.2678-2702 [Periódico revisado por pares]

United States: American Chemical Society

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