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Synthesis and Antiviral Activities of Methylenecyclopropane Analogs with 6-Alkoxy and 6-Alkylthio Substitutions That Exhibit Broad-Spectrum Antiviral Activity against Human Herpesviruses

Prichard, Mark N ; Williams, John D ; Komazin-Meredith, Gloria ; Khan, Atiyya R ; Price, Nathan B ; Jefferson, Geraldine M ; Harden, Emma A ; Hartline, Caroll B ; Peet, Norton P ; Bowlin, Terry L

Antimicrobial Agents and Chemotherapy, 2013-08, Vol.57 (8), p.3518-3527 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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Título:
Synthesis and Antiviral Activities of Methylenecyclopropane Analogs with 6-Alkoxy and 6-Alkylthio Substitutions That Exhibit Broad-Spectrum Antiviral Activity against Human Herpesviruses
Autor: Prichard, Mark N ; Williams, John D ; Komazin-Meredith, Gloria ; Khan, Atiyya R ; Price, Nathan B ; Jefferson, Geraldine M ; Harden, Emma A ; Hartline, Caroll B ; Peet, Norton P ; Bowlin, Terry L
Assuntos: Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Antiviral Agents - chemical synthesis ; Antiviral Agents - pharmacology ; Biological and medical sciences ; Cell Proliferation - drug effects ; Cells, Cultured ; Cyclopropanes ; Cyclopropanes - chemistry ; Cyclopropanes - pharmacology ; Cytomegalovirus ; Cytomegalovirus - drug effects ; Cytomegalovirus - enzymology ; DNA, Viral - analysis ; Drug Evaluation, Preclinical ; Epstein-Barr virus ; Guanine - analogs & derivatives ; Guanine - pharmacology ; Hepatitis B virus ; Herpesviridae ; Herpesviridae - drug effects ; Herpesviridae - physiology ; Herpesvirus 4, Human - drug effects ; Herpesvirus 4, Human - physiology ; Herpesvirus 6, Human - drug effects ; Herpesvirus 6, Human - physiology ; Herpesvirus 8, Human - drug effects ; Herpesvirus 8, Human - physiology ; Human cytomegalovirus ; Human herpesvirus 6 ; Human herpesvirus 8 ; Human immunodeficiency virus ; Humans ; Medical sciences ; Pharmacology. Drug treatments ; Phosphotransferases (Alcohol Group Acceptor) - chemistry ; Phosphotransferases (Alcohol Group Acceptor) - genetics ; Purine Nucleosides - chemical synthesis ; Purine Nucleosides - pharmacology ; Varicella-zoster virus ; Viral Plaque Assay ; Virus Replication - drug effects
É parte de: Antimicrobial Agents and Chemotherapy, 2013-08, Vol.57 (8), p.3518-3527
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Editor: Washington, DC: American Society for Microbiology
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Synthesis and Antiviral Activities of Methylenecyclopropane Analogs with 6-Alkoxy and 6-Alkylthio Substitutions That Exhibit Broad-Spectrum Antiviral Activity against Human Herpesviruses

Prichard, Mark N ; Williams, John D ; Komazin-Meredith, Gloria ; Khan, Atiyya R ; Price, Nathan B ; Jefferson, Geraldine M ; Harden, Emma A ; Hartline, Caroll B ; Peet, Norton P ; Bowlin, Terry L

Washington, DC: American Society for Microbiology

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