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Lithium carbonate in the treatment of drug-induced leukopenia in patients with solid tumors

Scanni, A ; Tomirotti, M ; Berra, S ; Licciardello, L ; Felicetta, I ; Bertolini, G ; Bregni, M

Tumori, 1980-12, Vol.66 (6), p.729-737 [Periódico revisado por pares]

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Título:
Lithium carbonate in the treatment of drug-induced leukopenia in patients with solid tumors
Autor: Scanni, A ; Tomirotti, M ; Berra, S ; Licciardello, L ; Felicetta, I ; Bertolini, G ; Bregni, M
Assuntos: Administration, Oral ; Adult ; Aged ; Antineoplastic Agents - adverse effects ; Clinical Trials as Topic ; Female ; Humans ; Leukocyte Count ; Leukopenia - chemically induced ; Leukopenia - drug therapy ; Lithium - administration & dosage ; Lithium - therapeutic use ; Middle Aged ; Neoplasms - blood ; Neoplasms - complications ; Neoplasms - drug therapy ; Random Allocation ; Time Factors
É parte de: Tumori, 1980-12, Vol.66 (6), p.729-737
Descrição: The authors report on the first part of an ongoing controlled trial (52 cases) on the evaluation of the effectiveness of Li2CO3 treatment of drug-induced leukopenia in patients with solid tumors. The results indicate that treatment with 750 mg/day per os of Li2CO3 for 7 days is capable of raising the leukocyte count to a highly significant extent, without serious side effects. The leukocytosis is due to an increase in neutrophil granulocytes.
Editor: United States
Idioma: Inglês

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