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The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients

Fonseca, Renata Fragelli ; Kawamura, Marcia Tie ; Oliveira, José Antônio ; Teixeira, Anselmo ; Alves, Gilda ; Carvalho, Maria da Glória da Costa

Memórias do Instituto Oswaldo Cruz, 2012-11, Vol.107 (7), p.953-954 [Periódico revisado por pares]

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Título:
The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients
Autor: Fonseca, Renata Fragelli ; Kawamura, Marcia Tie ; Oliveira, José Antônio ; Teixeira, Anselmo ; Alves, Gilda ; Carvalho, Maria da Glória da Costa
Assuntos: Adult ; Biopsy ; Brain Neoplasms - virology ; brain tumour ; Child ; Cohort Studies ; cytomegalovirus ; Cytomegalovirus - genetics ; Cytomegalovirus - immunology ; Cytomegalovirus Infections - complications ; Cytomegalovirus Infections - diagnosis ; DNA, Viral - analysis ; Female ; glioma ; Glioma - virology ; HCMV ; Humans ; Immediate-Early Proteins - analysis ; Immediate-Early Proteins - immunology ; Male ; Neoplasm Staging ; PARASITOLOGY ; Polymerase Chain Reaction ; Prevalence ; TROPICAL MEDICINE ; Young Adult
É parte de: Memórias do Instituto Oswaldo Cruz, 2012-11, Vol.107 (7), p.953-954
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Members of the Herpesviridae family have been implicated in a number of tumours in humans. At least 75% of the human population has had contact with cytomegalovirus (HCMV). In this work, we screened 75 Brazilian glioma biopsies for the presence of HCMV DNA sequences. HCMV DNA was detected in 36% (27/75) of the biopsies. It is possible that HCMV could be a co-factor in the evolution of brain tumours.
Editor: Brazil: Instituto Oswaldo Cruz, Ministério da Saúde
Idioma: Inglês;Português

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