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Phytochemical profile and qualification of biological activity of an isolated fraction of Bellis perennis

Costa Marques, Thiago H ; Santos De Melo, Cassio H ; Fonseca De Carvalho, Rusbene B ; Costa, Luciana M ; De Souza, Alexandre A ; David, Jorge M ; De Lima David, Juceni P ; De Freitas, Rivelilson M

Biological research, 2013, Vol.46 (3), p.231-238 [Periódico revisado por pares]

England: Sociedad de Biología de Chile

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Título:
Phytochemical profile and qualification of biological activity of an isolated fraction of Bellis perennis
Autor: Costa Marques, Thiago H ; Santos De Melo, Cassio H ; Fonseca De Carvalho, Rusbene B ; Costa, Luciana M ; De Souza, Alexandre A ; David, Jorge M ; De Lima David, Juceni P ; De Freitas, Rivelilson M
Assuntos: Acetylcholinesterase ; Acetylcholinesterase - drug effects ; Antioxidant ; Antioxidants - pharmacology ; Asteraceae - chemistry ; Asteraceae - classification ; Bellis perennis ; BIOLOGY ; Cholinesterase Inhibitors - pharmacology ; Flavonoid ; Flowers - chemistry ; Lipid Peroxidation - drug effects ; Plant Extracts - isolation & purification ; Plant Extracts - pharmacology
É parte de: Biological research, 2013, Vol.46 (3), p.231-238
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: This study describes the isolation and identification of apigenin-7-O-ghicopyranoside, a flavonoid isolated from the flowers of Bellis perennis L., Asteraceae, an species with a broad spectrum of biological activities. The in vitro antioxidant activity and the inhibition of the enzyme acetylcholinesterase were evaluated. The flavonoid showed strong in vitro antioxidant potential, because of the capacity of removal of hydroxyl radicals and nitric oxide, and also prevented the formation of thiobarbituric acid-reactive substances. These parameters were inhibited at the highest concentration of ApG at rates of 77.7%, 72% and 73.4%, respectively, in addition to inhibiting acetylcholinesterase, suggesting potential use in the treatment of neurodegenerative diseases.
Editor: England: Sociedad de Biología de Chile
Idioma: Inglês;Português

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Phytochemical profile and qualification of biological activity of an isolated fraction of Bellis perennis

Costa Marques, Thiago H ; Santos De Melo, Cassio H ; Fonseca De Carvalho, Rusbene B ; Costa, Luciana M ; De Souza, Alexandre A ; David, Jorge M ; De Lima David, Juceni P ; De Freitas, Rivelilson M

England: Sociedad de Biología de Chile

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