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Seroprevalence, cost per donation and reduction in blood supply due to positive and indeterminate results for infectious markers in a blood bank in Lima, Peru

Moya-Salazar, Jeel ; Ubidia-Incio, Roberto ; Incio-Grande, Maritza ; Blejer, Jorgelina L. ; Gonzalez, Carlos A.

Revista brasileira de hematologia e hemoterapia, 2017-04, Vol.39 (2), p.102-107

Brazil: Elsevier Editora Ltda

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  • Título:
    Seroprevalence, cost per donation and reduction in blood supply due to positive and indeterminate results for infectious markers in a blood bank in Lima, Peru
  • Autor: Moya-Salazar, Jeel ; Ubidia-Incio, Roberto ; Incio-Grande, Maritza ; Blejer, Jorgelina L. ; Gonzalez, Carlos A.
  • Assuntos: Blood donor ; HEMATOLOGY ; Indeterminate screening ; Infectious marker ; MEDICINE, RESEARCH & EXPERIMENTAL ; Original ; Seroprevalence
  • É parte de: Revista brasileira de hematologia e hemoterapia, 2017-04, Vol.39 (2), p.102-107
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
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  • Descrição: Safety in Transfusion Medicine is subject to regulations and government legislation within a total quality framework. The aim of this study was to evaluate the impact of seroprevalence and indeterminate results on lost units and cost per donation. A prospective cross-sectional study was performed in the Blood Bank and Transfusion Therapy Department of the Hospital Central de la Policia Nacional del Perú in Lima, Peru. All completed donations (replacement/voluntary) without complications were included in this study. Every donation met the institutional requirements and quality criteria of Programa Nacional de Hemoterapia y Bancos de Sangre (PRONAHEBAS). Data analysis was achieved using the Statistical Package for the Social Sciences. A total of 7723 donations were evaluated during 2014 and 2015 with 493 being seropositive (overall prevalence 5.25%) and 502 having indeterminate results (overall prevalence 5.35%). Thus total loss was 995units, 437.8L of blood and 49,750 US dollars. The most common seropositive infectious markers were the core antibody of hepatitis B virus (2.82%) and syphilis (1.02%), and the most common indeterminate results were Chagas disease (1.27%) and the core antibody of hepatitis B virus (1.26%). There was no significant change in the prevalence of seropositivity (p-value=0.243) or indeterminate results (p-value=0.227) over the two-year period of the study. A statistical correlation was found between the cost per lost donation and the most prevalent markers (rho=0.848; p-value=<0.001). Seroprevalence was lower than the regional mean, but the prevalence of indeterminate results was elevated causing a great impact on blood supply and economic losses to this institution.
  • Editor: Brazil: Elsevier Editora Ltda
  • Idioma: Inglês;Português
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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