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The social construction of the PrEP1519 study: conditions of possibility for advances in HIV/AIDS prevention

Barros, Sandra Garrido de ; Brasil, Sandra Assis ; Rossi, Thais Regis Aranha

Cadernos de saúde pública, 2023-01, Vol.39Suppl 1 (Suppl 1), p.e00201621-e00201621 [Periódico revisado por pares]

Brazil: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz

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  • Título:
    The social construction of the PrEP1519 study: conditions of possibility for advances in HIV/AIDS prevention
  • Autor: Barros, Sandra Garrido de ; Brasil, Sandra Assis ; Rossi, Thais Regis Aranha
  • Assuntos: Acquired Immunodeficiency Syndrome ; Acquired Immunodeficiency Syndrome - drug therapy ; Adolescent ; Anti-HIV Agents - therapeutic use ; Brazil - epidemiology ; Cohort Studies ; HIV Infections - drug therapy ; Humans ; Medical Sociology ; Pre-Exposure Prophylaxis ; Public Health Policies ; PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH ; Sexually Transmitted Diseases - epidemiology ; Teenagers
  • É parte de: Cadernos de saúde pública, 2023-01, Vol.39Suppl 1 (Suppl 1), p.e00201621-e00201621
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
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  • Descrição: This paper analyzed the genesis of the PrEP1519 study and feasibility conditions for its construction. A qualitative-approach study was conducted using the Bourdieusian sociology framework to reconstruct the dynamics of the social environment where PrEP1519 emerged during 2015-2018. A document analysis and ten in-depth interviews were carried out to analyze the trajectory of the project. Pre-exposure prophylaxis (PrEP) was introduced in Brazil as a public policy in 2017. The lack of scientific evidence available among the adolescent population led to the development of a demonstrative cohort study, associated with an intervention, aimed at combining the prevention and treatment of sexually transmitted infections at three sites in Brazil. PrEP1519 sought to generate evidence for global use and to help the Brazilian Ministry of Health apply PrEP among adolescents. The articulation of bureaucratic, scientific, and activist stakeholders enabled this study. The feasibility conditions for developing PrEP1519 included a favorable relationship of national organizations with international organizations, the favorable approach that public administrators had at the time towards new technologies and prevention strategies, the researchers' previous experience in studies with the target population or with PrEP, articulation efforts with social movements, civil society organizations, and other public agencies, and the integration between scientific institutions, which allowed using international resources and developing a response to the problem. Completing this study at a moment when conservatism advances in Brazil demands that the scientific community and activists closely monitor and take stances on PrEP to ensure its availability for adolescents as a public policy.
  • Editor: Brazil: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
  • Idioma: Inglês;Português

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