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The Human Cell Atlas

Regev, Aviv ; Teichmann, Sarah A ; Lander, Eric S ; Amit, Ido ; Benoist, Christophe ; Birney, Ewan ; Bodenmiller, Bernd ; Campbell, Peter ; Carninci, Piero ; Clatworthy, Menna ; Clevers, Hans ; Deplancke, Bart ; Dunham, Ian ; Eberwine, James ; Eils, Roland ; Enard, Wolfgang ; Farmer, Andrew ; Fugger, Lars ; Göttgens, Berthold ; Hacohen, Nir ; Haniffa, Muzlifah ; Hemberg, Martin ; Kim, Seung ; Klenerman, Paul ; Kriegstein, Arnold ; Lein, Ed ; Linnarsson, Sten ; Lundberg, Emma ; Lundeberg, Joakim ; Majumder, Partha ; Marioni, John C ; Merad, Miriam ; Mhlanga, Musa ; Nawijn, Martijn ; Netea, Mihai ; Nolan, Garry ; Pe'er, Dana ; Phillipakis, Anthony ; Ponting, Chris P ; Quake, Stephen ; Reik, Wolf ; Rozenblatt-Rosen, Orit ; Sanes, Joshua ; Satija, Rahul ; Schumacher, Ton N ; Shalek, Alex ; Shapiro, Ehud ; Sharma, Padmanee ; Shin, Jay W ; Stegle, Oliver ; Stratton, Michael ; Stubbington, Michael J T ; Theis, Fabian J ; Uhlen, Matthias ; van Oudenaarden, Alexander ; Wagner, Allon ; Watt, Fiona ; Weissman, Jonathan ; Wold, Barbara ; Xavier, Ramnik ; Yosef, Nir

eLife, 2017-12, Vol.6 [Periódico revisado por pares]

England: eLife Science Publications, Ltd

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Título:
The Human Cell Atlas
Autor: Regev, Aviv ; Teichmann, Sarah A ; Lander, Eric S ; Amit, Ido ; Benoist, Christophe ; Birney, Ewan ; Bodenmiller, Bernd ; Campbell, Peter ; Carninci, Piero ; Clatworthy, Menna ; Clevers, Hans ; Deplancke, Bart ; Dunham, Ian ; Eberwine, James ; Eils, Roland ; Enard, Wolfgang ; Farmer, Andrew ; Fugger, Lars ; Göttgens, Berthold ; Hacohen, Nir ; Haniffa, Muzlifah ; Hemberg, Martin ; Kim, Seung ; Klenerman, Paul ; Kriegstein, Arnold ; Lein, Ed ; Linnarsson, Sten ; Lundberg, Emma ; Lundeberg, Joakim ; Majumder, Partha ; Marioni, John C ; Merad, Miriam ; Mhlanga, Musa ; Nawijn, Martijn ; Netea, Mihai ; Nolan, Garry ; Pe'er, Dana ; Phillipakis, Anthony ; Ponting, Chris P ; Quake, Stephen ; Reik, Wolf ; Rozenblatt-Rosen, Orit ; Sanes, Joshua ; Satija, Rahul ; Schumacher, Ton N ; Shalek, Alex ; Shapiro, Ehud ; Sharma, Padmanee ; Shin, Jay W ; Stegle, Oliver ; Stratton, Michael ; Stubbington, Michael J T ; Theis, Fabian J ; Uhlen, Matthias ; van Oudenaarden, Alexander ; Wagner, Allon ; Watt, Fiona ; Weissman, Jonathan ; Wold, Barbara ; Xavier, Ramnik ; Yosef, Nir
Assuntos: Atlases as Topic ; Biochemistry ; Bioengineering ; Biologists ; Biology ; Book publishing ; Cancer ; cell atlas ; Cell Biology ; Cell cycle ; Cells (Biology) ; Computational and Systems Biology ; Computer engineering ; Computer science ; Criminal investigation ; Disease ; Diseases ; Eukaryotic Cells - classification ; Eukaryotic Cells - physiology ; Gene expression ; Genes ; Genomes ; Human Body ; Humans ; Immunology ; International Cooperation ; Laboratories ; lineage ; Medicin och hälsovetenskap ; Medicine ; Microscopy ; Open data ; Physiology ; Publishing industry ; Science Forum ; single-cell genomics ; Time
É parte de: eLife, 2017-12, Vol.6
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe to complete the 150-year-old effort to identify all cell types in the human body. The Human Cell Atlas Project is an international collaborative effort that aims to define all human cell types in terms of distinctive molecular profiles (such as gene expression profiles) and to connect this information with classical cellular descriptions (such as location and morphology). An open comprehensive reference map of the molecular state of cells in healthy human tissues would propel the systematic study of physiological states, developmental trajectories, regulatory circuitry and interactions of cells, and also provide a framework for understanding cellular dysregulation in human disease. Here we describe the idea, its potential utility, early proofs-of-concept, and some design considerations for the Human Cell Atlas, including a commitment to open data, code, and community.
Editor: England: eLife Science Publications, Ltd
Idioma: Inglês

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The Human Cell Atlas

England: eLife Science Publications, Ltd

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