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Anti-Inflammatory Herbal Extracts and Their Drug Discovery Perspective in Atopic Dermatitis

Jae-won Lee ; Eun-nam Kim ; Gil-saeng Jeong

Biomolecules & therapeutics, 2024, Vol.32 (1), p.25-37

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Título:
Anti-Inflammatory Herbal Extracts and Their Drug Discovery Perspective in Atopic Dermatitis
Autor: Jae-won Lee ; Eun-nam Kim ; Gil-saeng Jeong
Assuntos: Atopic dermatitis ; Herbal extracts ; Inflammatory cells ; Inflammatory molecules ; Keratinocytes ; Natural products
É parte de: Biomolecules & therapeutics, 2024, Vol.32 (1), p.25-37
Notas: The Korean Society of Applied Pharmacology
KISTI1.1003/JNL.JAKO202407557666699
Descrição: Atopic dermatitis (AD) is an allergic disorder characterized by skin inflammation. It is well known that the activation of various inflammatory cells and the generation of inflammatory molecules are closely linked to the development of AD. There is accumulating evidence demonstrating the beneficial effects of herbal extracts (HEs) on the regulation of inflammatory response in both in vitro and in vivo studies of AD. This review summarizes the anti-atopic effects of HEs and its associated underlying mechanisms, with a brief introduction of in vitro and in vivo experiment models of AD based on previous and recent studies. Thus, this review confirms the utility of HEs for AD therapy.
Editor: 한국응용약물학회
Idioma: Coreano

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