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Mindfulness-based interventions for people diagnosed with a current episode of an anxiety or depressive disorder: a meta-analysis of randomised controlled trials

Strauss, Clara ; Cavanagh, Kate ; Oliver, Annie ; Pettman, Danelle Laks, Jerson

PloS one, 2014-04, Vol.9 (4), p.e96110-e96110 [Peer Reviewed Journal]

United States: Public Library of Science

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Title:
Mindfulness-based interventions for people diagnosed with a current episode of an anxiety or depressive disorder: a meta-analysis of randomised controlled trials
Author: Strauss, Clara ; Cavanagh, Kate ; Oliver, Annie ; Pettman, Danelle
Laks, Jerson
Subjects: Active control ; Analysis ; Antidepressants ; Anxiety ; Anxiety Disorders - psychology ; Anxiety Disorders - therapy ; Behavior modification ; Biology and Life Sciences ; Care and treatment ; Clinical psychology ; Clinical trials ; Cognition & reasoning ; Cognitive ability ; Cognitive therapy ; Criteria ; Depression, Mental ; Depressive Disorder - psychology ; Depressive Disorder - therapy ; Diagnosis ; Diagnostic systems ; Health aspects ; Humans ; Intervention ; Medical diagnosis ; Medical ethics ; Medicine and Health Sciences ; Meditation ; Mental depression ; Meta-analysis ; Mindfulness ; Neuroses ; Obsessive compulsive disorder ; Physical Sciences ; Post traumatic stress disorder ; Psychotherapy ; Randomization ; Randomized Controlled Trials as Topic ; Recurrence ; Research and Analysis Methods ; Risk factors ; Risk reduction ; Stress ; Studies ; Systematic review
Is Part Of: PloS one, 2014-04, Vol.9 (4), p.e96110-e96110
Notes: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
Conceived and designed the experiments: CS KC. Performed the experiments: CS AO DP. Analyzed the data: CS AO DP. Contributed reagents/materials/analysis tools: CS. Wrote the paper: CS KC AO.
Competing Interests: The authors have declared that no competing interests exist.
Description: Mindfulness-based interventions (MBIs) can reduce risk of depressive relapse for people with a history of recurrent depression who are currently well. However, the cognitive, affective and motivational features of depression and anxiety might render MBIs ineffective for people experiencing current symptoms. This paper presents a meta-analysis of randomised controlled trials (RCTs) of MBIs where participants met diagnostic criteria for a current episode of an anxiety or depressive disorder. Post-intervention between-group Hedges g effect sizes were calculated using a random effects model. Moderator analyses of primary diagnosis, intervention type and control condition were conducted and publication bias was assessed. Twelve studies met inclusion criteria (n = 578). There were significant post-intervention between-group benefits of MBIs relative to control conditions on primary symptom severity (Hedges g = -0.59, 95% CI = -0.12 to -1.06). Effects were demonstrated for depressive symptom severity (Hedges g = -0.73, 95% CI = -0.09 to -1.36), but not for anxiety symptom severity (Hedges g = -0.55, 95% CI = 0.09 to -1.18), for RCTs with an inactive control (Hedges g = -1.03, 95% CI = -0.40 to -1.66), but not where there was an active control (Hedges g = 0.03, 95% CI = 0.54 to -0.48) and effects were found for MBCT (Hedges g = -0.39, 95% CI = -0.15 to -0.63) but not for MBSR (Hedges g = -0.75, 95% CI = 0.31 to -1.81). This is the first meta-analysis of RCTs of MBIs where all studies included only participants who were diagnosed with a current episode of a depressive or anxiety disorder. Effects of MBIs on primary symptom severity were found for people with a current depressive disorder and it is recommended that MBIs might be considered as an intervention for this population.
Publisher: United States: Public Library of Science
Language: English

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Mindfulness-based interventions for people diagnosed with a current episode of an anxiety or depressive disorder: a meta-analysis of randomised controlled trials

Strauss, Clara ; Cavanagh, Kate ; Oliver, Annie ; Pettman, Danelle Laks, Jerson

United States: Public Library of Science

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