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Risk of Bias in Reports of In Vivo Research: A Focus for Improvement

Macleod, Malcolm R ; Lawson McLean, Aaron ; Kyriakopoulou, Aikaterini ; Serghiou, Stylianos ; de Wilde, Arno ; Sherratt, Nicki ; Hirst, Theo ; Hemblade, Rachel ; Bahor, Zsanett ; Nunes-Fonseca, Cristina ; Potluru, Aparna ; Thomson, Andrew ; Baginskaite, Julija ; Baginskitae, Julija ; Egan, Kieren ; Vesterinen, Hanna ; Currie, Gillian L ; Churilov, Leonid ; Howells, David W ; Sena, Emily S

PLoS Biology, 2015-10, Vol.13 (10), p.e1002273-e1002273 [Periódico revisado por pares]

United States: Public Library of Science

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Título:
Risk of Bias in Reports of In Vivo Research: A Focus for Improvement
Autor: Macleod, Malcolm R ; Lawson McLean, Aaron ; Kyriakopoulou, Aikaterini ; Serghiou, Stylianos ; de Wilde, Arno ; Sherratt, Nicki ; Hirst, Theo ; Hemblade, Rachel ; Bahor, Zsanett ; Nunes-Fonseca, Cristina ; Potluru, Aparna ; Thomson, Andrew ; Baginskaite, Julija ; Baginskitae, Julija ; Egan, Kieren ; Vesterinen, Hanna ; Currie, Gillian L ; Churilov, Leonid ; Howells, David W ; Sena, Emily S
Assuntos: Animal diseases ; Animals ; Bias ; Biological markers ; Biological Science Disciplines - methods ; Biological Science Disciplines - trends ; Biomedical research ; Biomedical Research - methods ; Biomedical Research - standards ; Biomedical Research - trends ; Councils ; Data Accuracy ; Experiments ; Funding ; Guidelines as Topic ; Higher education ; Humans ; Impact factors ; Journal Impact Factor ; Medical research ; Periodicals as Topic - trends ; Physiological aspects ; Publication Bias ; Quality ; Quality Improvement ; Science ; Selection Bias ; Studies ; United Kingdom
É parte de: PLoS Biology, 2015-10, Vol.13 (10), p.e1002273-e1002273
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
Conceived and designed the experiments: MRM ESS HV GLC KE DWH LC. Performed the experiments: ALM AK SS AdW NS TH RH ZB CNF AP AT JB. Analyzed the data: ALM AK ZB JB HV ESS GLC LC. Wrote the paper: MRM ESS DWH GLC HV KE ALM AK SS NS TH JB LC.
MRM is a member of the PLOS Medicine Editorial Board.
Descrição: The reliability of experimental findings depends on the rigour of experimental design. Here we show limited reporting of measures to reduce the risk of bias in a random sample of life sciences publications, significantly lower reporting of randomisation in work published in journals of high impact, and very limited reporting of measures to reduce the risk of bias in publications from leading United Kingdom institutions. Ascertainment of differences between institutions might serve both as a measure of research quality and as a tool for institutional efforts to improve research quality.
Editor: United States: Public Library of Science
Idioma: Inglês

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Risk of Bias in Reports of In Vivo Research: A Focus for Improvement

United States: Public Library of Science

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