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Crystalline nephropathies

Herlitz, Leal C ; D'Agati, Vivette D ; Markowitz, Glen S

Archives of pathology & laboratory medicine (1976), 2012-07, Vol.136 (7), p.713-720 [Periódico revisado por pares]

United States: College of American Pathologists

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  • Título:
    Crystalline nephropathies
  • Autor: Herlitz, Leal C ; D'Agati, Vivette D ; Markowitz, Glen S
  • Assuntos: Calcium Oxalate - metabolism ; Crystals ; Hematuria ; Humans ; Kidney - metabolism ; Kidney - pathology ; Kidney diseases ; Kidney Diseases - metabolism ; Kidney Diseases - pathology ; Leukocytes ; Light ; Metabolism ; Microscopy ; Multiple myeloma ; Patients
  • É parte de: Archives of pathology & laboratory medicine (1976), 2012-07, Vol.136 (7), p.713-720
  • Descrição: The kidney is a favored site for crystal deposition because of the high concentration of ions and molecules reached at the level of the renal tubules in the course of filtration. This review focuses on crystalline nephropathies in 4 broad categories: (1) dysproteinemia- associated, (2) drug-induced, (3) calcium-containing, and (4) metabolic or genetic. To provide a framework for accurate identification of the diverse types of crystals encountered in the kidney in order to formulate an appropriate differential diagnosis and guide additional testing and treatment. Review of pertinent published literature along with practical experience gained in a high-volume renal pathology laboratory. Accurate identification of crystals encountered in the kidney is essential in detecting conditions ranging from hematologic malignancy to drug toxicity to metabolic disorders. Detailed clinical-pathologic correlation is needed to accurately diagnose the underlying cause of most crystalline nephropathies.
  • Editor: United States: College of American Pathologists
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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