Idioma:

Pharmacokinetics of carprofen and firocoxib for medication control in racing greyhounds

Morris, TH ; Paine, SW ; Zahra, PW ; Li, EC ; Colgan, SA ; Karamatic, SL

Australian veterinary journal, 2020-12, Vol.98 (12), p.578-585 [Periódico revisado por pares]

Texto completo disponível

Citações Citado por

Título:
Pharmacokinetics of carprofen and firocoxib for medication control in racing greyhounds
Autor: Morris, TH ; Paine, SW ; Zahra, PW ; Li, EC ; Colgan, SA ; Karamatic, SL
Assuntos: 4-Butyrolactone - analogs & derivatives ; Animal welfare ; Animals ; Carbazoles ; carprofen ; Dogs ; firocoxib ; greyhound ; Meat ; Pharmacokinetics ; racing ; Sulfones ; Urine
É parte de: Australian veterinary journal, 2020-12, Vol.98 (12), p.578-585
Descrição: Animals used in sport should be treated as required to ensure animal welfare but any such use of medication should also be controlled to ensure integrity. Pharmacokinetic studies on groups of six greyhounds were performed to measure plasma and urine levels of carprofen and firocoxib to inform medication control advice. Using the standard methodology for medication control the Irrelevant Plasma Concentration was determined as 20 and 2 ng/mL for carprofen and firocoxib, respectively. The Irrelevant Urine Concentration was also determined as 0.3 and 2 ng/mL for carprofen and firocoxib, respectively. These Irrelevant Plasma and Urine Concentrations will allow laboratory Screening Limits, Detection Times and Withdrawal Time advice to be determined and publicised by regulators of greyhound racing. The Screening Limits will also inform Recommended Limits of Detection if meat‐containing residues of these medications are fed to greyhounds.
Editor: Melbourne: Wiley Publishing Asia Pty Ltd
Idioma: Inglês

Links

Voltar para lista de resultados

Anterior Resultado 10 Avançar Ir para próxima página