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Neural identification of Type 1 Diabetes Mellitus for care and forecasting of risk events

Sanchez, Oscar D. ; Alanis, Alma Y. ; Ruiz Velázquez, E. ; Valencia Murillo, Roberto

Expert systems with applications, 2021-11, Vol.183, p.115367, Article 115367 [Periódico revisado por pares]

New York: Elsevier Ltd

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  • Título:
    Neural identification of Type 1 Diabetes Mellitus for care and forecasting of risk events
  • Autor: Sanchez, Oscar D. ; Alanis, Alma Y. ; Ruiz Velázquez, E. ; Valencia Murillo, Roberto
  • Assuntos: Algorithms ; Automatic control ; Control algorithms ; Control theory ; Diabetes ; Diabetes mellitus ; Extended Kalman filter ; Glucose ; Hyperglycemia ; Hypoglycemia ; Identification ; Insulin ; Multi-step ahead predictor ; Neural network ; Neural networks ; RHONN ; Support systems ; Type 1 Diabetes Mellitus
  • É parte de: Expert systems with applications, 2021-11, Vol.183, p.115367, Article 115367
  • Descrição: Glucose–insulin models, testing glucose sensors and support systems for health care decisions play an important role in synthesis of glucose control algorithms. In this work we propose an online glucose–insulin identification using the Recurrent High Order Neural Network (RHONN). Then, the model obtained is used to predict n-steps forward of glucose levels, also by RHONN. The used data for identification is from a Type 1 Diabetes Mellitus (T1DM) patient, it was collected from the Continuous Monitoring Glucose System (CMGS) by MiniMed Inc ® and an insulin pump by Paradigm Real-time Insulin Pump ®. RHONN is trained online by Extended Kalman Filter (EKF). The results suggest that it is possible to make a prediction of up to 35 min in the future, which it would help to prevent risky events (hypoglycemia and hyperglycemia). Also shows that, it could be directly connected to a CGMS to help the patient improve the glucose control and even an automatic glucose control algorithm. The proposed Neural Network shows good performance compared to baseline methods in terms of evaluation criteria. •With RHOON we perform identification of the dynamics of blood glucose.•35 min of blood glucose were predicted with RHONN.•Training for the identification and prediction network was done online.•RHONN predictions are compared with three methods.
  • Editor: New York: Elsevier Ltd
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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