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Nickel Metallomics: General Themes Guiding Nickel Homeostasis

Banci, Lucia

Metal ions in life sciences, 2013, Vol.12, p.375-416

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Título:
Nickel Metallomics: General Themes Guiding Nickel Homeostasis
Autor: Banci, Lucia
Assuntos: accessory proteins ; Homeostasis ; Inorganic chemistry ; Life sciences: general issues ; Metalloproteins - metabolism ; Nickel - metabolism ; nickel homeostasis ; nickel metallochaperones ; nickel metalloenzymes ; Physiology ; transcription factors ; transporters
É parte de: Metal ions in life sciences, 2013, Vol.12, p.375-416
Notas: Please cite as: Met. Ions Life Sci. 12 (2013) 375–416
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Descrição: The nickel metallome describes the distribution and speciation of nickel within the cells of organisms that utilize this element. This distribution is a consequence of nickel homeostasis, which includes import, storage, and export of nickel, incorporation into metalloenzymes, and the modulation of these and associated cellular systems through nickel-regulated transcription. In this chapter, we review the current knowledge of the most common nickel proteins in prokaryotic organisms with a focus on their coordination environments. Several underlying themes emerge upon review of these nickel systems, which illustrate the common principles applied by nature to shape the nickel metallome of the cell.
Títulos relacionados: Metal Ions in Life Sciences
Editor: The Netherlands: Springer Netherlands
Idioma: Inglês

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