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Carbon-core silver-shell nanodots as sensitizers for phototherapy and radiotherapy

Kleinauskas, Andrius ; Rocha, Sandra ; Sahu, Sushant ; Sun, Ya-Ping ; Juzenas, Petras

Nanotechnology, 2013-08, Vol.24 (32), p.325103-325103 [Periódico revisado por pares]

Bristol: IOP Publishing

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Título:
Carbon-core silver-shell nanodots as sensitizers for phototherapy and radiotherapy
Autor: Kleinauskas, Andrius ; Rocha, Sandra ; Sahu, Sushant ; Sun, Ya-Ping ; Juzenas, Petras
Assuntos: Biological ; Cancer ; Carbon ; Carbon - chemistry ; Catalysis - radiation effects ; Cell Death - drug effects ; Cell Death - radiation effects ; Cell Line ; Cell Survival - drug effects ; Cell Survival - radiation effects ; Condensed matter: structure, mechanical and thermal properties ; Cross-disciplinary physics: materials science; rheology ; Exact sciences and technology ; Fullerenes and related materials; diamonds, graphite ; Humans ; Hydrodynamics ; In vitro testing ; Materials science ; Nanocomposites ; Nanocrystalline materials ; Nanomaterials ; Nanoparticles ; Nanoparticles - toxicity ; Nanoparticles - ultrastructure ; Nanoscale materials and structures: fabrication and characterization ; Nanostructure ; Nanotechnology ; Photocatalysis ; Photosensitizer ; Photosensitizing Agents - pharmacology ; Phototherapy ; Physics ; Radiation effects on specific materials ; Radiocatalysis ; Radiosensitizer ; Radiotherapy ; Silver ; Silver - chemistry ; Specific materials ; Spectrometry, Fluorescence ; Structure of solids and liquids; crystallography ; Ultraviolet Rays
É parte de: Nanotechnology, 2013-08, Vol.24 (32), p.325103-325103
Notas: ObjectType-Article-1
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Descrição: Spherical carbon nanoparticles (carbon nanodots) with a silver shell were investigated as potential sensitizing agents. The cytotoxicity of the combination of ultraviolet radiation or x-rays with the nanodots was examined in cancer cells in vitro. The cell viability decreased following the exposure to the radiation. The carbon nanodots enhanced the radiation effects by significantly reducing the amount of surviving cells compared to that of the cells exposed only to the radiation. Carbon-core silver-shell nanodots can be proposed as a bimodal sensitization platform for biological and medicinal applications employing non-ionizing or ionizing radiation.
Editor: Bristol: IOP Publishing
Idioma: Inglês

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Carbon-core silver-shell nanodots as sensitizers for phototherapy and radiotherapy

Kleinauskas, Andrius ; Rocha, Sandra ; Sahu, Sushant ; Sun, Ya-Ping ; Juzenas, Petras

Bristol: IOP Publishing

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