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Male
hypogonadism
Basaria, Shehzad, Dr
The Lancet (British edition), 2014-04, Vol.383 (9924), p.1250-1263
[Periódico revisado por pares]
Kidlington: Elsevier Ltd
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Título:
Male
hypogonadism
Autor:
Basaria, Shehzad, Dr
Assuntos:
Administration, Cutaneous
;
Administration, Oral
;
Affect - drug effects
;
Androgens
;
Androgens - administration & dosage
;
Biological and medical sciences
;
Bone density
;
Bone Density - drug effects
;
Cardiovascular Diseases - chemically induced
;
Chemotherapy
;
Cognition Disorders - drug therapy
;
Contraindications
;
Diabetes Mellitus - etiology
;
Early Diagnosis
;
Enzymes
;
Fertility
;
Gels
;
General aspects
;
Genotype & phenotype
;
Humans
;
Hypogonadism - diagnosis
;
Hypogonadism - etiology
;
Hypogonadism - therapy
;
Hypothalamo-Hypophyseal System - physiology
;
Infertility
;
Insulin Resistance - physiology
;
Internal Medicine
;
Lipids - blood
;
Male
;
Medical sciences
;
Men
;
Muscle Strength - drug effects
;
Mutation
;
Patient Satisfaction
;
Polycythemia - chemically induced
;
Prostatic Neoplasms - chemically induced
;
Quality of Life
;
Reproductive technologies
;
Sexual Dysfunction, Physiological - drug therapy
;
Sleep
;
Sleep Apnea Syndromes - chemically induced
;
Sperm
;
Spermatogenesis
;
Tablets
;
Testis - physiology
;
Testosterone
;
Testosterone - administration & dosage
;
Testosterone - deficiency
;
Trauma
É parte de:
The Lancet (British edition), 2014-04, Vol.383 (9924), p.1250-1263
Notas:
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ObjectType-Feature-1
ObjectType-Literature Review-3
Descrição:
Summary
Male
hypogonadism is a clinical syndrome that results from failure to produce physiological concentrations of testosterone, normal amounts of sperm, or both. Hypogonadism may arise from testicular disease (primary hypogonadism) or dysfunction of the hypothalamic-pituitary unit (secondary hypogonadism). Clinical presentations vary dependent on the time of onset of androgen deficiency, whether the defect is in testosterone production or spermatogenesis, associated genetic factors, or history of androgen therapy. The clinical diagnosis of hypogonadism is made on the basis of signs and symptoms consistent with androgen deficiency and low morning testosterone concentrations in serum on multiple occasions. Several testosterone-replacement therapies are approved for treatment and should be selected according to the patient's preference, cost, availability, and formulation-specific properties. Contraindications to testosterone-replacement therapy include prostate and breast cancers, uncontrolled congestive heart failure, severe lower-urinary-tract symptoms, and erythrocytosis. Treatment should be monitored for benefits and adverse effects.
Editor:
Kidlington: Elsevier Ltd
Idioma:
Inglês
Links
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