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BIOLOGICAL ACTIVITIES OF KAEMPFEROL: EFFECT OF CYCLODEXTRINS COMPLEXATION ON THE PROPERTIES OF KAEMPFEROL

Mercader-Ros, M T ; Lucas-Abellán, C ; tea, M I ; Serrano-Martínez, A ; Gabaldón, J A ; Núñez-Delicado, E

Chemical physics research journal, 2013-07, Vol.6 (3/4), p.209-209

Hauppauge: Nova Science Publishers, Inc

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  • Título:
    BIOLOGICAL ACTIVITIES OF KAEMPFEROL: EFFECT OF CYCLODEXTRINS COMPLEXATION ON THE PROPERTIES OF KAEMPFEROL
  • Autor: Mercader-Ros, M T ; Lucas-Abellán, C ; tea, M I ; Serrano-Martínez, A ; Gabaldón, J A ; Núñez-Delicado, E
  • Assuntos: Antioxidants ; Bioavailability ; Biosynthesis ; Complexation ; Cyclodextrins ; Enzymes ; Flavonoids ; Food ; Free radicals ; Fruits ; Functional foods & nutraceuticals ; Metabolites ; Plants (organisms) ; Polyphenols ; Solubility ; Studies ; Sugar ; Wines
  • É parte de: Chemical physics research journal, 2013-07, Vol.6 (3/4), p.209-209
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: The flavonoid kaempferol is a yellow compound with a low molecular weight (MW: 286.24 g/mol) that is commonly found in plant-derived foods and in plants used in traditional medicine. Because the enzymes involved in the biosynthesis of kaempferol are relatively common in the plant kingdom, it is not surprising that this flavonoid is widely distributed in plants. Kaempferol is relatively abundant in apples, grapes, gingko biloba, onions, leeks, citrus fruits, red wines, tea, cruciferous vegetables, and some edible berries. Many preclinical studies have shown that kaempferol and some glycosides of kaempferol have extensive pharmacological activities, including antioxidant, antiinflammatory, anticancer, antimicrobial, cardioprotective, neuroprotective, antidiabetic, anti-osteoporotic, estrogenic/antiestrogenic, anxiolytic, analgesic and antiallergic activities. The main problem is its low water solubility and its stability against various factors such as oxygen, light and temperature. In recent years, complexation with cyclodextrins has successfully been used to improve the solubility, chemical stability and bioavailability of a number of poorly soluble phenolics compounds, such as resveratrol, mirycetin and quercetin.
  • Editor: Hauppauge: Nova Science Publishers, Inc
  • Idioma: Inglês
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