Idioma:

Differences in the toxin profiles of Alexandrium ostenfeldii (Dinophyceae) strains isolated from different geographic origins: Evidence of paralytic toxin, spirolide, and gymnodimine

Salgado, Pablo ; Riobó, Pilar ; Rodríguez, Francisco ; Franco, José M. ; Bravo, Isabel

Toxicon (Oxford), 2015-09, Vol.103, p.85-98 [Periódico revisado por pares]

England: Elsevier Ltd

Texto completo disponível

Citações Citado por

Enviar para

Título:
Differences in the toxin profiles of Alexandrium ostenfeldii (Dinophyceae) strains isolated from different geographic origins: Evidence of paralytic toxin, spirolide, and gymnodimine
Autor: Salgado, Pablo ; Riobó, Pilar ; Rodríguez, Francisco ; Franco, José M. ; Bravo, Isabel
Assuntos: Alexandrium ; Alexandrium ostenfeldii ; Chile ; Chromatography, High Pressure Liquid ; Dinoflagellates ; Dinoflagellida - classification ; Dinoflagellida - isolation & purification ; Dinophyceae ; Equivalence ; Gymnodimine ; Heterocyclic Compounds, 3-Ring - isolation & purification ; Heterocyclic Compounds, 3-Ring - toxicity ; Hydrocarbons, Cyclic - isolation & purification ; Hydrocarbons, Cyclic - toxicity ; Imines - isolation & purification ; Imines - toxicity ; Marine Toxins - analysis ; Marine Toxins - toxicity ; Oceans and Seas ; Origins ; Paralytic toxin ; Phylogeny ; Phylogeography ; Poisoning ; Saxitoxin - analogs & derivatives ; Saxitoxin - isolation & purification ; Saxitoxin - toxicity ; Seas ; Shellfish ; Shellfish Poisoning - etiology ; Shellfish Poisoning - pathology ; Spiro Compounds - isolation & purification ; Spiro Compounds - toxicity ; Spirolide ; Strain ; Toxin profile ; Toxins
É parte de: Toxicon (Oxford), 2015-09, Vol.103, p.85-98
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Among toxin-producing dinoflagellates of the genus Alexandrium, Alexandrium ostenfeldii is the only species able to produce paralytic shellfish poisoning (PSP) toxins, spirolides (SPXs) and gymnodimines (GYMs). In this study we characterized and compared three A. ostenfeldii strains isolated from the Baltic, Mediterranean, and southern Chile Seas with respect to their toxin profiles, morphology, and phylogeny. Toxin analyses by HPLC–FD and LC–HRMS revealed differences in the toxin profiles of the three strains. The PSP toxin profiles of the southern Chile and Baltic strains were largely the same and included gonyautoxin (GTX)-3, GTX-2, and saxitoxin (STX), although the total PSP toxin content of the Chilean strain (105.83 ± 72.15 pg cell−1) was much higher than that of the Baltic strain (4.04 ± 1.93 pg cell−1). However, the Baltic strain was the only strain that expressed detectable amounts of analogues of GYM-A and GYM-B/-C (48.27 ± 26.12 pg GYM-A equivalents cell−1). The only toxin expressed by the Mediterranean strain was 13-desmethyl SPX-C (13dMeC; 2.85 ± 4.76 pg cell−1). Phylogenetic analysis based on the LSU rRNA showed that the studied strains belonged to distinct molecular clades. The toxin profiles determined in this study provide further evidence of the taxonomic complexity of this species. •Chilean and Baltic strains showed the same PSP toxin profiles.•PSP toxins of Chilean strain were much higher than Baltic strain.•The Baltic strain produced also analogues of GYM-A and GYM-B/-C.•Mediterranean strain only produced 13-desmethyl SPX-C.
Editor: England: Elsevier Ltd
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Anterior Resultado 4 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Differences in the toxin profiles of Alexandrium ostenfeldii (Dinophyceae) strains isolated from different geographic origins: Evidence of paralytic toxin, spirolide, and gymnodimine

Salgado, Pablo ; Riobó, Pilar ; Rodríguez, Francisco ; Franco, José M. ; Bravo, Isabel

England: Elsevier Ltd

Buscando em bases de dados remotas. Favor aguardar.