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The Impact of Gender on Tumour Stage in In-House Complications and Choice of Urinary Diversion: Results of the Austrian Cystectomy Registry

Gschliesser, Tanja ; Eredics, Klaus ; Berger, Ingrid ; Szelinger, Michael ; Klingler, Hans Christoph ; Colombo, Thomas ; Ponholzer, Anton ; Plas, Eugen ; Grubmüller, Karl ; Dunzinger, Michael ; Jeschke, Klaus ; Würnschimmel, Erich ; Krause, Frens Steffen ; Shariat, Sharokh ; Leeb, Karl ; Pelzer, Alexandre ; Riedl, Claus ; Rauchenwald, Michael ; Hübner, Wilhelm ; Brössner, Clemens ; Madersbacher, Stephan

Urologia internationalis, 2017-01, Vol.99 (4), p.429-435 [Periódico revisado por pares]

Basel, Switzerland

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Título:
The Impact of Gender on Tumour Stage in In-House Complications and Choice of Urinary Diversion: Results of the Austrian Cystectomy Registry
Autor: Gschliesser, Tanja ; Eredics, Klaus ; Berger, Ingrid ; Szelinger, Michael ; Klingler, Hans Christoph ; Colombo, Thomas ; Ponholzer, Anton ; Plas, Eugen ; Grubmüller, Karl ; Dunzinger, Michael ; Jeschke, Klaus ; Würnschimmel, Erich ; Krause, Frens Steffen ; Shariat, Sharokh ; Leeb, Karl ; Pelzer, Alexandre ; Riedl, Claus ; Rauchenwald, Michael ; Hübner, Wilhelm ; Brössner, Clemens ; Madersbacher, Stephan
Assuntos: Aged ; Austria ; Chi-Square Distribution ; Clinical Decision-Making ; Cystectomy - adverse effects ; Databases, Factual ; Female ; Healthcare Disparities ; Humans ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Staging ; Odds Ratio ; Original Paper ; Patient Selection ; Postoperative Complications - etiology ; Prospective Studies ; Registries ; Risk Factors ; Sex Factors ; Time Factors ; Treatment Outcome ; Urinary Bladder Neoplasms - pathology ; Urinary Bladder Neoplasms - surgery ; Urinary Diversion - adverse effects ; Urinary Diversion - methods
É parte de: Urologia internationalis, 2017-01, Vol.99 (4), p.429-435
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Introduction and Objectives: Bladder cancer is characterized by gender-dependent disparities. To further address this issue, we analysed a prospective, multicentre cystectomy registry. Methods: An online database was developed that included patient demographics, intra/perioperative data, surgical data and in-house complications. Results: Four hundred fifty-eight patients (112 [24.5%] women and 346 [75.5%] men) were analysed. Men and women were comparable regarding age (mean 68 years), body mass index (mean 26.5) and the mean Charlson score (4.8). Women had more advanced tumour-stages (pT3/pT4; women: 57.1%; men: 48.1%). The rate of incontinent urinary diversion was higher in women (83.1%) than in men (60.2%) and in a multivariate analysis, the strongest predictors were M+ status (OR 11.2), female gender (OR 6.9) and age (OR 6.5). Women had a higher intraoperative blood transfusion rate. The overall rate of in-house complications was similar in both genders (men: 32.0%, women: 32.6%). Severe (Clavien-Dindo grade >2) medical (women: 6.3%; men: 5.2%) and surgical (women: 21.5%; men: 14.4%) in-house complications, however, were more frequent in women. Conclusions: This multicentre registry demonstrates several gender-related differences in patients undergoing radical cystectomy. The higher transfusion rate, the rare use of orthotopic bladder substitutes and the higher in-house complication rate underline the higher complexity of this procedure in women.
Editor: Basel, Switzerland
Idioma: Inglês

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The Impact of Gender on Tumour Stage in In-House Complications and Choice of Urinary Diversion: Results of the Austrian Cystectomy Registry

Basel, Switzerland

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