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Initial results of the FUSION-X-US prototype combining 3D automated breast ultrasound and digital breast tomosynthesis

Schaefgen, Benedikt ; Heil, Joerg ; Barr, Richard G. ; Radicke, Marcus ; Harcos, Aba ; Gomez, Christina ; Stieber, Anne ; Hennigs, André ; von Au, Alexandra ; Spratte, Julia ; Rauch, Geraldine ; Rom, Joachim ; Schütz, Florian ; Sohn, Christof ; Golatta, Michael

European radiology, 2018-06, Vol.28 (6), p.2499-2506 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

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Título:
Initial results of the FUSION-X-US prototype combining 3D automated breast ultrasound and digital breast tomosynthesis
Autor: Schaefgen, Benedikt ; Heil, Joerg ; Barr, Richard G. ; Radicke, Marcus ; Harcos, Aba ; Gomez, Christina ; Stieber, Anne ; Hennigs, André ; von Au, Alexandra ; Spratte, Julia ; Rauch, Geraldine ; Rom, Joachim ; Schütz, Florian ; Sohn, Christof ; Golatta, Michael
Assuntos: Accuracy ; Adult ; Aged ; Automation ; Biopsy ; Breast ; Breast Neoplasms - diagnostic imaging ; Breast Neoplasms - pathology ; Calcinosis - diagnostic imaging ; Data acquisition ; Diagnosis, Differential ; Diagnostic Radiology ; Diagnostic systems ; Equipment Design ; Feasibility Studies ; Female ; Humans ; Image acquisition ; Image Interpretation, Computer-Assisted - methods ; Image quality ; Imaging ; Imaging, Three-Dimensional - instrumentation ; Imaging, Three-Dimensional - methods ; Internal Medicine ; Interventional Radiology ; Lesions ; Mammography - instrumentation ; Mammography - methods ; Medicine ; Medicine & Public Health ; Middle Aged ; Multimodal Imaging - instrumentation ; Multimodal Imaging - methods ; Neuroradiology ; Prospective Studies ; Radiology ; Sensitivity and Specificity ; Ultrasonic imaging ; Ultrasonography, Mammary - instrumentation ; Ultrasonography, Mammary - methods ; Ultrasound
É parte de: European radiology, 2018-06, Vol.28 (6), p.2499-2506
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
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Descrição: Purpose To determine the feasibility of a prototype device combining 3D-automated breast ultrasound (ABVS) and digital breast tomosynthesis in a single device to detect and characterize breast lesions. Methods In this prospective feasibility study, the FUSION-X-US prototype was used to perform digital breast tomosynthesis and ABVS in 23 patients with an indication for tomosynthesis based on current guidelines after clinical examination and standard imaging. The ABVS and tomosynthesis images of the prototype were interpreted separately by two blinded experts. The study compares the detection and BI-RADS® scores of breast lesions using only the tomosynthesis and ABVS data from the FUSION-X-US prototype to the results of the complete diagnostic workup. Results Image acquisition and processing by the prototype was fast and accurate, with some limitations in ultrasound coverage and image quality. In the diagnostic workup, 29 solid lesions (23 benign, including three cases with microcalcifications, and six malignant lesions) were identified. Using the prototype, all malignant lesions were detected and classified as malignant or suspicious by both investigators. Conclusion Solid breast lesions can be localized accurately and fast by the Fusion-X-US system. Technical improvements of the ultrasound image quality and ultrasound coverage are needed to further study this new device. Key Points The p rototy p e combines tomosynthesis and automated 3D-ultrasound (ABVS) in one device. It allows accurate detection of malignant lesions, directly correlating tomosynthesis and ABVS data. The diagnostic evaluation of the p rototy p e-acquired data was inter p reter-inde p endent. The p rototy p e p rovides a time-efficient and technically reliable diagnostic p rocedure. The combination of tomosynthesis and ABVS is a p romising diagnostic a pp roach.
Editor: Berlin/Heidelberg: Springer Berlin Heidelberg
Idioma: Inglês

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Initial results of the FUSION-X-US prototype combining 3D automated breast ultrasound and digital breast tomosynthesis

Schaefgen, Benedikt ; Heil, Joerg ; Barr, Richard G. ; Radicke, Marcus ; Harcos, Aba ; Gomez, Christina ; Stieber, Anne ; Hennigs, André ; von Au, Alexandra ; Spratte, Julia ; Rauch, Geraldine ; Rom, Joachim ; Schütz, Florian ; Sohn, Christof ; Golatta, Michael

Berlin/Heidelberg: Springer Berlin Heidelberg

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