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High low‐density lipoprotein cholesterol as an independent risk factor for coronary restenosis in hemodialysis patients undergoing percutaneous coronary interventions

Hasegawa, Shoko ; Nakano, Toshiaki ; Mukai, Yasushi ; Matsukuma, Yuta ; Yotsueda, Ryusuke ; Tsuchimoto, Akihiro ; Fujisaki, Kiichiro ; Tsuruya, Kazuhiko ; Tsutsui, Hiroyuki ; Kitazono, Takanari

Therapeutic apheresis and dialysis, 2021-06, Vol.25 (3), p.296-303 [Periódico revisado por pares]

Kyoto, Japan: John Wiley & Sons Australia, Ltd

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  • Título:
    High low‐density lipoprotein cholesterol as an independent risk factor for coronary restenosis in hemodialysis patients undergoing percutaneous coronary interventions
  • Autor: Hasegawa, Shoko ; Nakano, Toshiaki ; Mukai, Yasushi ; Matsukuma, Yuta ; Yotsueda, Ryusuke ; Tsuchimoto, Akihiro ; Fujisaki, Kiichiro ; Tsuruya, Kazuhiko ; Tsutsui, Hiroyuki ; Kitazono, Takanari
  • Assuntos: cardiovascular disease ; Cholesterol ; coronary restenosis ; Hemodialysis ; lipids ; Low density lipoproteins ; Medical research ; Medicine, Experimental ; Transluminal angioplasty
  • É parte de: Therapeutic apheresis and dialysis, 2021-06, Vol.25 (3), p.296-303
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: HD patients have been reported to have a higher risk of restenosis after percutaneous coronary intervention (PCI). The aim of this study was to investigate the risk factors of coronary restenosis in HD patients. We enrolled 54 HD patients (mean age: 66.5 ± 10.1 years; 72.2% men; mean HD duration: 3.7 years), who received PCI and follow‐up coronary angiography. Of the patients, 22 (40.7%) had restenosis within 3 to 12 months of PCI. Univariate logistic analysis showed low‐density lipoprotein cholesterol (LDL‐C)/high‐density lipoprotein cholesterol (HDL‐C) ratio, LDL‐C, non‐HDL‐C, and history of major adverse cardiovascular events were significantly associated with coronary restenosis (OR]: 1.89, 1.27, 1.22, and 5.79, respectively). Multivariate analysis showed that LDL‐C was significantly associated with coronary restenosis (OR: 1.43). These data suggest that LDL‐C is an independent risk factor for coronary restenosis in HD patients undergoing PCI, and strict lipid management may be required.
  • Editor: Kyoto, Japan: John Wiley & Sons Australia, Ltd
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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