Idioma:

Burden of Diarrhoeagenic Escherichia coli in Santa Rosa, Guatemala in active health‐services surveillance during 2008–2009 and 2014–2015

Jarquin, Claudia ; Morales, Oneida ; McCracken, John P. ; Lopez, Maria R. ; Lopez, Beatriz ; Reyes, Lisette ; Gómez, Gerardo A. ; Bryan, Joe P. ; Peruski, Leonard F. ; Parsons, Michele B. ; Pattabiraman, Vaishnavi

Tropical medicine & international health, 2022-04, Vol.27 (4), p.408-417 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

Texto completo disponível

Citações Citado por

Enviar para

Título:
Burden of Diarrhoeagenic Escherichia coli in Santa Rosa, Guatemala in active health‐services surveillance during 2008–2009 and 2014–2015
Autor: Jarquin, Claudia ; Morales, Oneida ; McCracken, John P. ; Lopez, Maria R. ; Lopez, Beatriz ; Reyes, Lisette ; Gómez, Gerardo A. ; Bryan, Joe P. ; Peruski, Leonard F. ; Parsons, Michele B. ; Pattabiraman, Vaishnavi
Assuntos: Adolescent ; Adult ; Biochemical tests ; Central America ; Child ; Child, Preschool ; Children ; DEC ; Diarrhea ; Diarrhea - epidemiology ; diarrhoea ; E coli ; EPEC ; Epidemiology ; Escherichia coli ; Escherichia coli - genetics ; Escherichia coli Infections - epidemiology ; ETEC ; Feces ; gastroenteritis ; Guatemala - epidemiology ; Health care ; Health care facilities ; Health surveillance ; Humans ; Infant ; Infant, Newborn ; Middle Aged ; Patients ; Risk analysis ; Risk factors ; Rosa ; STEC ; Virulence ; Virulence factors ; Young Adult
É parte de: Tropical medicine & international health, 2022-04, Vol.27 (4), p.408-417
Notas: Funding information
Good Health and Wellbeing.
Sustainable Development Goal
The work was supported in part by Cooperative Agreement No. UO1 GH000028‐02 from the CDC. The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the CDC.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Objective To describe the epidemiology of laboratory‐confirmed Diarrhoeagenic Escherichia coli (DEC) cases from active facility‐based surveillance in Guatemala. Methods We collected clinical and risk factor data on enrolled patients (aged 0–52 years) with acute diarrhoea at government healthcare facilities (1 hospital and 6 clinics) in Santa Rosa, Guatemala, during 2008–2009 and 2014–2015. Stool samples were analysed, E. coli identified through culture and biochemical tests, PCR amplification of genes encoding pathotype‐specific virulence factors identified specific DEC pathotypes. Healthcare‐seeking adjusted incidence rates were calculated. Results A total of 3041 diarrhoea cases were captured by surveillance (647 hospitalisations (H), 2394 clinic visits (CV)); general E. coli prevalence was 17.9%. DEC pathotypes were identified in 19% (n = 95/497) and 21% (n = 450/2113) in diarrhoea H and CV, respectively. Enteropathogenic E. coli (EPEC) was most frequently isolated (8.2% (n = 41) in diarrhoea H, 12.0% (n = 255) in diarrhoea CV), followed by ETEC (6.8% (n = 34) in H, 6% (n = 128) in CV) and STEC (0.6% (n = 3) in H, 0.6% (n = 13) in CV). We did not find evidence of a difference in severity between DEC and non‐DEC diarrhoea. Incidence of DEC clinic visits and hospitalisations was 648.0 and 29.3, respectively, per 10,000 persons aged ≤5 years and 36.8 and 0.4, respectively, per 10,000 persons aged >5 years. Conclusions DEC pathotypes, especially EPEC and ETEC, were detected frequently from patients presenting with diarrhoeal illness in Santa Rosa, Guatemala. Our findings suggest that preventive interventions should be prioritised for young children.
Editor: England: Blackwell Publishing Ltd
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Burden of Diarrhoeagenic Escherichia coli in Santa Rosa, Guatemala in active health‐services surveillance during 2008–2009 and 2014–2015

Jarquin, Claudia ; Morales, Oneida ; McCracken, John P. ; Lopez, Maria R. ; Lopez, Beatriz ; Reyes, Lisette ; Gómez, Gerardo A. ; Bryan, Joe P. ; Peruski, Leonard F. ; Parsons, Michele B. ; Pattabiraman, Vaishnavi

England: Blackwell Publishing Ltd

Buscando em bases de dados remotas. Favor aguardar.