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Comparison between exercise therapy and non-hydrolyzed collagen (UC-II) in functionality and quality of life in women with knee osteoarthritis: A randomized controlled clinical trial

Santana, Érika Thatyana Nascimento ; da Cunha Machado, Saulo ; Brandão Lima, Viviane Nascimento ; DeSantana Filho, Valter Joviniano ; dos Santos Maciel, Leonardo Yung ; de Farias Neto, Jader Pereira ; Coutinho, Henrique Douglas Melo ; Martins, Natália ; Monteiro da Silva Júnior, Walderi ; Quintans Júnior, Lucindo J.

Wiener Klinische Wochenschrift, 2023-06, Vol.135 (11-12), p.291-300 [Peer Reviewed Journal]

Vienna: Springer Vienna

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Title:
Comparison between exercise therapy and non-hydrolyzed collagen (UC-II) in functionality and quality of life in women with knee osteoarthritis: A randomized controlled clinical trial
Author: Santana, Érika Thatyana Nascimento ; da Cunha Machado, Saulo ; Brandão Lima, Viviane Nascimento ; DeSantana Filho, Valter Joviniano ; dos Santos Maciel, Leonardo Yung ; de Farias Neto, Jader Pereira ; Coutinho, Henrique Douglas Melo ; Martins, Natália ; Monteiro da Silva Júnior, Walderi ; Quintans Júnior, Lucindo J.
Subjects: Collagen ; Endocrinology ; Exercise Therapy - methods ; Female ; Gastroenterology ; Humans ; Internal Medicine ; Medicine ; Medicine & Public Health ; Original Article ; Osteoarthritis, Knee - diagnosis ; Osteoarthritis, Knee - therapy ; Pain ; Pneumology/Respiratory System ; Postural Balance ; Quality of Life ; Time and Motion Studies ; Treatment Outcome
Is Part Of: Wiener Klinische Wochenschrift, 2023-06, Vol.135 (11-12), p.291-300
Notes: ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
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Description: Summary Background Knee osteoarthritis (OA) is characterized by a progressive degeneration of cartilage and menisci, leading to pain and locomotor disability. Here, we aimed to assess the effect of an exercise protocol and the oral use of non-hydrolyzed collagen (UC-II) on the functionality and quality of life of women with knee OA. Material and methods Individuals were divided into three groups (CG [control group]; MG [medication group]; EG [exercise group]). In the CG there was no intervention, while MG received an oral dose (1 capsule/day) of UC-II and the EG held 12 sessions of an exercise protocol. Results In the functionality tests (6-min walk test, 6MWT and timed up and go test [TUG]) the EG ( p  < 0.001/ p  = 0.020) and MG ( p  = 0.010/ p  = 0.010) revealed a significant improvement when compared to the CG. In the analysis of quality of life by WOMAC, a significant improvement was found only in the EG ( p  = 0.030) when compared to the CG; the same happened in the stiffness domain (EG, p  = 0.010), despite in the pain domain, both the EG ( p  < 0.001) and the MG ( p  = 0.060) were better than the CG. Conclusion Data obtained here reveal that an exercise protocol and UC-II have similar effects for functionality, despite exercise being superior in promoting the quality of life score.
Publisher: Vienna: Springer Vienna
Language: English

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Comparison between exercise therapy and non-hydrolyzed collagen (UC-II) in functionality and quality of life in women with knee osteoarthritis: A randomized controlled clinical trial

Vienna: Springer Vienna

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