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The thymus: what’s normal and what’s not? Problem-solving with MRI

Greenish, D. ; Evans, C.J. ; Khine, C.K. ; Rodrigues, J.C.L.

Clinical radiology, 2023-12, Vol.78 (12), p.885-894 [Periódico revisado por pares]

Elsevier Ltd

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  • Título:
    The thymus: what’s normal and what’s not? Problem-solving with MRI
  • Autor: Greenish, D. ; Evans, C.J. ; Khine, C.K. ; Rodrigues, J.C.L.
  • É parte de: Clinical radiology, 2023-12, Vol.78 (12), p.885-894
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-3
    content type line 23
    ObjectType-Review-1
  • Descrição: Anterior mediastinal masses can be difficult to characterise on computed tomography (CT) due to the wide spectrum of normal appearances of thymic tissue as well as the challenge of differentiating between benign and malignant pathologies. Additionally, attenuation of cystic mediastinal lesions can be misinterpreted on CT due to varying attenuation values. Anecdotally, non-vascular magnetic resonance imaging (MRI) of the thorax is underutilised across radiology departments in the UK, but has been shown to improve diagnostic certainty and reduce unnecessary surgical intervention. T2-weighted MRI is useful in confirming the cystic nature of lesions, whereas chemical shift techniques can be utilised to document the presence of macroscopic and intra-cellular fat and thus help distinguish between benign and malignant pathologies. In this review article, we present a practical approach to using MRI for the characterisation of anterior mediastinal lesions based on our clinical experience in a UK district general hospital. •Thymic lesions can be difficult to characterise on CT as attenuation can vary.•Non-vascular MRI is an underutilised trouble-shooting tool for thymic pathology.•Chemical shift MRI helps distinguishing benign from malignant thymic lesions.
  • Editor: Elsevier Ltd
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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