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Nanoscalar Structures of Spray-Dried Zein Microcapsules and in Vitro Release Kinetics of the Encapsulated Lysozyme As Affected by Formulations

Zhong, Qixin ; Jin, Minfeng

Journal of agricultural and food chemistry, 2009-05, Vol.57 (9), p.3886-3894 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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Título:
Nanoscalar Structures of Spray-Dried Zein Microcapsules and in Vitro Release Kinetics of the Encapsulated Lysozyme As Affected by Formulations
Autor: Zhong, Qixin ; Jin, Minfeng
Assuntos: Animal, plant, fungal and microbial proteins, edible seaweeds and food yeasts ; Anti-Infective Agents - administration & dosage ; antimicrobial properties ; Aroma and flavouring agent industries ; Biological and medical sciences ; Capsules ; Desiccation - methods ; encapsulation ; food analysis ; Food Chemistry/Biochemistry ; food composition ; Food industries ; food matrix ; food processing ; food processing quality ; Fundamental and applied biological sciences. Psychology ; in vitro studies ; Kinetics ; lysozyme ; Microcapsules ; Microscopy, Electron, Scanning ; model food systems ; Muramidase - administration & dosage ; Muramidase - analysis ; Muramidase - chemistry ; nanoscalar structures ; nanotechnology ; shelf life ; Solutions ; spray drying ; Thymol - administration & dosage ; Thymol - analysis ; Thymol - chemistry ; zein ; Zein - administration & dosage ; Zein - analysis ; Zein - chemistry
É parte de: Journal of agricultural and food chemistry, 2009-05, Vol.57 (9), p.3886-3894
Notas: http://dx.doi.org/10.1021/jf803951a
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Descrição: Sustained release of antimicrobials may be a viable solution to enhance the bioavailability during the shelf life of food products. In this work, spray-drying was used to encapsulate a model antimicrobial of lysozyme in corn zein. The effects of zein/lysozyme (20:1 to 4:1) and zein/thymol (1:0 to 4:1) ratios on the microstructures of microcapsules and in vitro release profiles of the encapsulated lysozyme were investigated. In all cases, less lysozyme was released at higher pH, resulting from stronger molecular attraction between zein and lysozyme. Nanoscalar matrix structures of microcapsules were correlated with release characteristics of the encapsulated lysozyme. At intermediate zein/lysozyme (10:1) and zein/thymol (50:1) ratios, microcapsules had a continuous matrix structure and showed sustained release (11.1−65.3%) of lysozyme at pH 6 over 49 days. This work may be developed into practical food grade delivery systems of antimicrobials.
Editor: Washington, DC: American Chemical Society
Idioma: Inglês

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Nanoscalar Structures of Spray-Dried Zein Microcapsules and in Vitro Release Kinetics of the Encapsulated Lysozyme As Affected by Formulations

Zhong, Qixin ; Jin, Minfeng

Washington, DC: American Chemical Society

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