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Serial CT and MRI of ischaemic cerebral infarcts : frequency and clinical impact of haemorrhagic transformation

MAYER, T. E ; SCHULTE-ALTERDORNEBURG, G ; DROSTE, D. W ; BRÜCKMANN, H

Neuroradiology, 2000-04, Vol.42 (4), p.233-239 [Periódico revisado por pares]

Berlin: Springer

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Título:
Serial CT and MRI of ischaemic cerebral infarcts : frequency and clinical impact of haemorrhagic transformation
Autor: MAYER, T. E ; SCHULTE-ALTERDORNEBURG, G ; DROSTE, D. W ; BRÜCKMANN, H
Assuntos: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Brain - pathology ; Brain Ischemia - diagnosis ; Cerebral Hemorrhage - complications ; Cerebral Hemorrhage - diagnosis ; Cerebral Infarction - complications ; Cerebral Infarction - diagnosis ; Child ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Middle Aged ; Neurology ; Prognosis ; Prospective Studies ; Severity of Illness Index ; Tomography, X-Ray Computed ; Vascular diseases and vascular malformations of the nervous system
É parte de: Neuroradiology, 2000-04, Vol.42 (4), p.233-239
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: The frequency, predisposing factors and clinical consequences of haemorrhagic infarcts and damaged blood-brain barrier as shown by contrast enhancement (CE) in ischaemic cerebral infarcts are controversial. We prospectively compared the sensitivity of CT and MRI to haemorrhagic transformation (HT) and CE. We also wished to investigate the clinical significance of HT and factors possibly associated with it. We studied 36 patients with acute ischaemic infarcts in the middle cerebral artery territory during the first 2 weeks after the ictus. After CT and rating of the neurological deficit on admission, serial examinations with clinical neuromonitoring, contrast-enhanced CT and MRI were done on the same day. The occurrence and severity of HT were correlated with CE, stroke mechanism, infarct size, development of neurological deficits and antithrombotic treatment. The frequency of HT detected by MRI was 80%. CE usually preceded HT or was seen simultaneously. MRI had a higher sensitivity than CT to HT and CE. Severity of HT was positively correlated with infarct size (P < 0.01). HT had no influence on patient's neurological status. Neither the type of antithrombotic treatment nor the stroke mechanism was associated with the severity of HT. No parenchymal haemorrhage occurred.
Editor: Berlin: Springer
Idioma: Inglês

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Serial CT and MRI of ischaemic cerebral infarcts : frequency and clinical impact of haemorrhagic transformation

MAYER, T. E ; SCHULTE-ALTERDORNEBURG, G ; DROSTE, D. W ; BRÜCKMANN, H

Berlin: Springer

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