Idioma:

Carbonyl Sulfide:Mediated Prebiotic Formation of Peptides

Leman, Luke ; Orgel, Leslie ; Ghadiri, M. Reza

Science (American Association for the Advancement of Science), 2004-10, Vol.306 (5694), p.283-286 [Periódico revisado por pares]

Washington, DC: American Association for the Advancement of Science

Texto completo disponível

Citações Citado por

Enviar para

Título:
Carbonyl Sulfide:Mediated Prebiotic Formation of Peptides
Autor: Leman, Luke ; Orgel, Leslie ; Ghadiri, M. Reza
Assuntos: Addition polymerization ; Amino acids ; Amino Acids - chemistry ; Anaerobiosis ; Analytical, structural and metabolic biochemistry ; Biochemistry ; Biological and medical sciences ; Borates ; Chemical properties ; Chemical reactions ; Condensation ; Cyclization ; Dipeptides - chemistry ; Evolution, Chemical ; Fundamental and applied biological sciences. Psychology ; General aspects, investigation methods ; Hydrolysis ; Magnetic Resonance Spectroscopy ; Oligopeptides - chemistry ; Organic Chemistry ; Origin of life ; Oxidation ; Oxidation-Reduction ; Peptides ; Phenylalanine - chemistry ; Polymerization ; Prebiotic chemistry ; Prebiotics ; Proteins ; Serine - chemistry ; Sulfides ; Sulfur Oxides - chemistry ; Temperature ; Thermodynamics ; Thiocarbamates ; Thiocarbamates - chemistry
É parte de: Science (American Association for the Advancement of Science), 2004-10, Vol.306 (5694), p.283-286
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Article-2
ObjectType-Feature-1
Descrição: Almost all discussions of prebiotic chemistry assume that amino acids, nucleotides, and possibly other monomers were first formed on the Earth or brought to it in comets and meteorites, and then condensed nonenzymatically to form oligomeric products. However, attempts to demonstrate plausibly prebiotic polymerization reactions have met with limited success. We show that carbonyl sulfide (COS), a simple volcanic gas, brings about the formation of peptides from amino acids under mild conditions in aqueous solution. Depending on the reaction conditions and additives used, exposure of α-amino acids to COS generates peptides in yields of up to 80% in minutes to hours at room temperature.
Editor: Washington, DC: American Association for the Advancement of Science
Idioma: Inglês

Links

Voltar para lista de resultados

Anterior Resultado 7 Avançar Ir para próxima página

Realização: Logos de Redes Sociais:

Carbonyl Sulfide:Mediated Prebiotic Formation of Peptides

Leman, Luke ; Orgel, Leslie ; Ghadiri, M. Reza

Washington, DC: American Association for the Advancement of Science

Buscando em bases de dados remotas. Favor aguardar.